Mesocarb
Encyclopedia
Mesocarb is a stimulant
drug which was developed in the USSR in the 1970s. It has been shown to act as a dopamine reuptake inhibitor
which is slower acting but longer lasting and less neurotoxic than dextroamphetamine
.
Mesocarb is still used for a variety of applications; these include counteracting the sedative effects of benzodiazepine
drugs, increasing workload capacity and cardiovascular function, treatment of ADHD and hyperactivity in children, as a nootropic
, and as a drug to enhance resistance to extremely cold temperatures. It is also listed as having antidepressant
and anticonvulsant
properties.
Mesocarb is sold in Russia as 5 milligram tablets under the brand name Sydnocarb. Hydroxylated metabolites can be detected in urine for up to 10 days after consumption, reflecting a relatively long half-life.
Mesocarb is almost unknown in the western world and is neither used in medicine or studied scientifically to any great extent outside Russia and other countries in the former Soviet Union. It has however been added to the list of drugs under international control and is illegal in most countries, despite its multiple therapeutic applications and the lack of significant abuse potential seen in clinical practice.
sydnone imine
. It has the amphetamine-backbone present, except that the RN has a complicated imine side-chain present.
Stimulant
Stimulants are psychoactive drugs which induce temporary improvements in either mental or physical function or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others...
drug which was developed in the USSR in the 1970s. It has been shown to act as a dopamine reuptake inhibitor
Dopamine reuptake inhibitor
A dopamine reuptake inhibitor is a type of drug that acts as a reuptake inhibitor for the neurotransmitter dopamine by blocking the action of the dopamine transporter...
which is slower acting but longer lasting and less neurotoxic than dextroamphetamine
Dextroamphetamine
Dextroamphetamine is a psychostimulant drug which is known to produce increased wakefulness and focus as well as decreased fatigue and decreased appetite....
.
Mesocarb is still used for a variety of applications; these include counteracting the sedative effects of benzodiazepine
Benzodiazepine
A benzodiazepine is a psychoactive drug whose core chemical structure is the fusion of a benzene ring and a diazepine ring...
drugs, increasing workload capacity and cardiovascular function, treatment of ADHD and hyperactivity in children, as a nootropic
Nootropic
Nootropics , also referred to as smart drugs, brain steroids, memory enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration...
, and as a drug to enhance resistance to extremely cold temperatures. It is also listed as having antidepressant
Antidepressant
An antidepressant is a psychiatric medication used to alleviate mood disorders, such as major depression and dysthymia and anxiety disorders such as social anxiety disorder. According to Gelder, Mayou &*Geddes people with a depressive illness will experience a therapeutic effect to their mood;...
and anticonvulsant
Anticonvulsant
The anticonvulsants are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder, since many seem to act as mood stabilizers, and in the treatment of neuropathic pain. The goal of an...
properties.
Mesocarb is sold in Russia as 5 milligram tablets under the brand name Sydnocarb. Hydroxylated metabolites can be detected in urine for up to 10 days after consumption, reflecting a relatively long half-life.
Mesocarb is almost unknown in the western world and is neither used in medicine or studied scientifically to any great extent outside Russia and other countries in the former Soviet Union. It has however been added to the list of drugs under international control and is illegal in most countries, despite its multiple therapeutic applications and the lack of significant abuse potential seen in clinical practice.
Chemistry
Mesocarb is a mesoionicMesoionic
Mesoionic chemical compounds are dipolar five- or six- membered heterocyclic compounds in which both the negative and the positive charges are delocalized...
sydnone imine
Sydnone imine
Sydnone imine is a mesoionic heterocyclic aromatic chemical compound. Sydnone imine is the imine of sydnone where the keto functional group of sydnone has been replaced with an imine group. A sydnone imine substructure can be found in the stimulant drugs feprosidnine and mesocarb and the...
. It has the amphetamine-backbone present, except that the RN has a complicated imine side-chain present.