Michaelis–Becker reaction
Encyclopedia
The Michaelis–Becker reaction is the reaction of a hydrogen phosphonate with a base, followed by a nucleophilic substitution
of phosphorus on an alkyl halide, to afford an alkyl phosphonate. Yields of this reaction are often lower than the corresponding Michaelis-Arbuzov reaction
.
Nucleophilic substitution
In organic and inorganic chemistry, nucleophilic substitution is a fundamental class of reactions in which an electron nucleophile selectively bonds with or attacks the positive or partially positive charge of an atom or a group of atoms called the leaving group; the positive or partially positive...
of phosphorus on an alkyl halide, to afford an alkyl phosphonate. Yields of this reaction are often lower than the corresponding Michaelis-Arbuzov reaction
Michaelis-Arbuzov reaction
The Michaelis–Arbuzov reaction is the chemical reaction of a trialkyl phosphite and an alkyl halide to form a phosphonate....
.