Mode of action
Encyclopedia
Historically, pesticide
s have often been classified according to their chemical groups and this is useful for understanding the properties of a given compound. However, it is the Mode of Action (MoA) group which possibly represents the most useful pesticide classification for biologists. For example, MoA at the top of entries in the Pesticide Manual may be something like: 'FRAC G1', 'IRAC 2A' or HRAC G' - what do these mean? From a pesticide industry point of view, one of the most important threats to product sustainability and innovation is the onset of resistance. Research-based companies collaborate (under the auspices of CropLife International
) in order to develop better understanding of MoA mechanisms and thus create a "common good" by mitigating the onset of resistance.
Currently, there are four specialist committees:
Understanding pesticide MoA is important for:
in Pharmaceuticals
This Pesticide
s stub has been reproduced from the IPARC MoA page with permission from the author.
Pesticide
Pesticides are substances or mixture of substances intended for preventing, destroying, repelling or mitigating any pest.A pesticide may be a chemical unicycle, biological agent , antimicrobial, disinfectant or device used against any pest...
s have often been classified according to their chemical groups and this is useful for understanding the properties of a given compound. However, it is the Mode of Action (MoA) group which possibly represents the most useful pesticide classification for biologists. For example, MoA at the top of entries in the Pesticide Manual may be something like: 'FRAC G1', 'IRAC 2A' or HRAC G' - what do these mean? From a pesticide industry point of view, one of the most important threats to product sustainability and innovation is the onset of resistance. Research-based companies collaborate (under the auspices of CropLife International
CropLife International
CropLife International is an international federation of agricultural biotechnology companies. It was previously known as Global Crop Protection Federation and International Group of National Associations of Manufacturers of Agrochemical Products....
) in order to develop better understanding of MoA mechanisms and thus create a "common good" by mitigating the onset of resistance.
Currently, there are four specialist committees:
- Fungicide Resistance Action Committee (FRAC)
- Insecticide Resistance Action Committee (IRAC)
- Herbicide Resistance Action Committee (HRAC)
- Rodenticide Resistance Action Committee (RRAC)
Understanding pesticide MoA is important for:
- Resistance management
- Describing the symptoms and physiology of the method by which a substance is effective, thus …
- Determining its likely effects (and often speed of action) on the target pest.
- Providing a convenient classification of pesticides for biologists
See also
Mechanism of actionMechanism of action
In pharmacology, the term mechanism of action refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect...
in Pharmaceuticals
This Pesticide
Pesticide
Pesticides are substances or mixture of substances intended for preventing, destroying, repelling or mitigating any pest.A pesticide may be a chemical unicycle, biological agent , antimicrobial, disinfectant or device used against any pest...
s stub has been reproduced from the IPARC MoA page with permission from the author.