Mouse Phenome Database
Encyclopedia
The Mouse Phenome Database (MPD) is a web-accessible database of strain
characterization data for the laboratory mouse, to facilitate translational research
for human health and disease. MPD characterizes phenotype
as well as genotype
, and provides tools for online analysis. Most phenotype data are in the form of strain surveys (comparisons of 10-40 commonly used mouse strains) and cover such areas as hematology
, bone mineral density, cholesterol
levels, endocrine function, and aging processes. Genotype data are primarily in the form of single-nucleotide polymorphisms. Data are contributed by participating scientists or downloaded from public resources. The MPD was begun in 2000, is funded by grants from the National Institutes of Health
and other sources, and is headquartered at The Jackson Laboratory
.
Strain
Strain can refer to:* Strain , variants of plants, viruses or bacteria; or an inbred animal used for experimental purposes* Strain , a chemical stress of a molecule...
characterization data for the laboratory mouse, to facilitate translational research
Translational research
Translational research is a way of thinking about and conducting scientific research to make the results of research applicable to the population under study and is practised in the natural and biological, behavioural, and social sciences...
for human health and disease. MPD characterizes phenotype
Phenotype
A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior...
as well as genotype
Genotype
The genotype is the genetic makeup of a cell, an organism, or an individual usually with reference to a specific character under consideration...
, and provides tools for online analysis. Most phenotype data are in the form of strain surveys (comparisons of 10-40 commonly used mouse strains) and cover such areas as hematology
Hematology
Hematology, also spelled haematology , is the branch of biology physiology, internal medicine, pathology, clinical laboratory work, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases...
, bone mineral density, cholesterol
Cholesterol
Cholesterol is a complex isoprenoid. Specifically, it is a waxy steroid of fat that is produced in the liver or intestines. It is used to produce hormones and cell membranes and is transported in the blood plasma of all mammals. It is an essential structural component of mammalian cell membranes...
levels, endocrine function, and aging processes. Genotype data are primarily in the form of single-nucleotide polymorphisms. Data are contributed by participating scientists or downloaded from public resources. The MPD was begun in 2000, is funded by grants from the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
and other sources, and is headquartered at The Jackson Laboratory
Jackson Laboratory
The Jackson Laboratory was founded in Bar Harbor, Maine in 1929 by former University of Maine and University of Michigan president C. C. Little under the name Roscoe B...
.