Multifocal fibrosclerosis
Encyclopedia
Multifocal fibrosclerosis and idiopathic fibrosclerosis are disorders of unknown aetiology, characterised by fibrous lesion
Lesion
A lesion is any abnormality in the tissue of an organism , usually caused by disease or trauma. Lesion is derived from the Latin word laesio which means injury.- Types :...

s (co-)occurring at a variety of sites. Known manifestations include retroperitoneal fibrosis
Retroperitoneal fibrosis
Retroperitoneal fibrosis or Ormond's disease is a disease featuring the proliferation of fibrous tissue in the retroperitoneum, the compartment of the body containing the kidneys, aorta, renal tract and various other structures. It may present with lower back pain, renal failure, hypertension, deep...

, mediastinal fibrosis
Mediastinal fibrosis
Mediastinal fibrosis is a rare late complication of histoplasmosis. It is characterized by invasive, calcified fibrosis centered on lymph nodes that block major vessels and airways....

 and Riedel's struma of the thyroid
Thyroid
The thyroid gland or simply, the thyroid , in vertebrate anatomy, is one of the largest endocrine glands. The thyroid gland is found in the neck, below the thyroid cartilage...

.
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