Mycobacterium phlei
Encyclopedia
Mycobacterium phlei is an acid-fast
Acid-fast
Acid-fastness is a physical property of certain bacteria, specifically their resistance to decolorization by acids during staining procedures.Acid-fast organisms are difficult to characterize using standard microbiological techniques Acid-fastness is a physical property of certain bacteria,...

 bacteria
Bacteria
Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...

 of the genus Mycobacterium
Mycobacterium
Mycobacterium is a genus of Actinobacteria, given its own family, the Mycobacteriaceae. The genus includes pathogens known to cause serious diseases in mammals, including tuberculosis and leprosy...

. They are named this way because they contain mycolic acid
Mycolic acid
Mycolic acids are long fatty acids found in the cell walls of the mycolata taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis. They form the major component of the cell wall of mycolata species...

s, which is also the reason that simple staining or Gram staining does not give good results with this microbe. In fact, they cover their cell bodies with mycolic acid
Mycolic acid
Mycolic acids are long fatty acids found in the cell walls of the mycolata taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis. They form the major component of the cell wall of mycolata species...

, which makes them one of the hardest genus of bacteria to kill.

Of the genus Mycobacterium, M. phlei, is characterized as one of the fast-growing mycobacteria. On egg media and sheep's blood agar, the colonies are flat with a distinctive pigmentation ranging from deep yellow to orange.

M. phlei has only occasionally been isolated in human infections, and patients infected with M. phlei generally respond well to anti-mycobacterial therapy.

M. phlei, has been known to have up to 73% GC content, also making its Tm very high
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