N'-Formylkynurenine
Encyclopedia
N′-Formylkynurenine is an intermediate in the catabolism
of tryptophan
. It is a formylated
derivative of kynurenine
.
Catabolism
Catabolism is the set of metabolic pathways that break down molecules into smaller units and release energy. In catabolism, large molecules such as polysaccharides, lipids, nucleic acids and proteins are broken down into smaller units such as monosaccharides, fatty acids, nucleotides, and amino...
of tryptophan
Tryptophan
Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG...
. It is a formylated
Formylation
Formylation is a type of posttranslational modification in which a formyl group is added to the N-terminus of a protein....
derivative of kynurenine
Kynurenine
L-Kynurenine is a metabolite of the amino acid L-tryptophan used in the production of niacin. It has been associated with tics.Kynureninase catabolizes the conversion of kynurenine into anthranilic acid while kynurenine-oxoglutarate transaminase catabolizes its conversion into kynurenic acid...
.
See also
- Indoleamine 2,3-dioxygenaseIndoleamine 2,3-dioxygenaseIndoleamine-pyrrole 2,3-dioxygenase is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells...
- KynurenineKynurenineL-Kynurenine is a metabolite of the amino acid L-tryptophan used in the production of niacin. It has been associated with tics.Kynureninase catabolizes the conversion of kynurenine into anthranilic acid while kynurenine-oxoglutarate transaminase catabolizes its conversion into kynurenic acid...