N-acetylglucosamine-1-phosphate transferase
Encyclopedia
N-acetylglucosamine-1-phosphate transferase is a transferase
Transferase
In biochemistry, a transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another . For example, an enzyme that catalyzed this reaction would be a transferase:In this example, A would be the donor, and B would be the acceptor...

 enzyme.

It is associated with the following conditions:
  • mucolipidosis II alpha/beta (I-cell disease
    I-cell disease
    Inclusion-cell disease, also referred to as mucolipidosis II , is part of the lysosomal storage disease family and results from a defective phosphotransferase . This enzyme transfers phosphate to mannose residues on specific proteins, and serves as a marker for them to be targeted to lysosomes...

    ) - GNPTAB
  • mucolipidosis III alpha/beta (pseudo-Hurler polydystrophy
    Pseudo-Hurler polydystrophy
    Pseudo-Hurler polydystrophy, also referred to as mucolipidosis III , is a lysosomal storage disease closely related to I-cell disease...

    ) - GNPTAB
  • mucolipidosis III gamma - GNPTG


In melanocytic cells GNPTG gene expression may be regulated by MITF
Microphthalmia-associated transcription factor
Microphthalmia-associated transcription factor is a basic helix-loop-helix leucine zipper transcription factor involved in melanocyte and osteoclast development.-Clinical significance:...

.

External links

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