NPR3
Encyclopedia
Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), also known as NPR3, is an atrial natriuretic peptide receptor
. In humans it is encoded by the NPR3 gene
.
s elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.
Atrial natriuretic peptide receptor
A atrial natriuretic peptide receptor is a receptor for atrial natriuretic peptide.- Mechanism :NPRA and NPRB are linked to guanylyl cyclases, while NPRAC is G-protein-linked and is a "clearance receptor" that acts to internalise and destroy the ligand....
. In humans it is encoded by the NPR3 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
The family of natriuretic peptideNatriuretic peptide
Natriuretic peptide refers to a peptide which induces natriuresis .Types include:* Atrial natriuretic peptide: atria* Brain natriuretic peptide: ventricles in humans, brains in pigs* C-type natriuretic peptide...
s elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.