Nextbio
Encyclopedia
NextBio is a privately owned software company that provides a platform for drug companies and life science researchers to search, discover, and share knowledge across public and proprietary data. It was co-founded by Saeid Akhtari, Ilya Kupershmidt and Mostafa Ronaghi
in 2004 and based in Cupertino, California
, USA.
The NextBio Platform is an ontology
-based semantic framework that connects highly heterogeneous data and textual information. The semantic framework is based on gene, tissue, disease and compound ontologies. This framework contains information from different organisms, platforms, data types and research areas that is integrated into and correlated within a single searchable environment using proprietary algorithms. It provides a unified interface for researchers to formulate and test new hypotheses across vast collections of experimental data.
According to the company, the enterprise version of the NextBio platform is being used in life science research and development and drug development by researchers and clinicians at: Merck Pharmaceutical
, Johnson & Johnson
Pharmaceutical Research & Development, L.L.C., Celgene
, Genzyme
, Eli Lilly and Company
, and Regeneron Pharmaceuticals. This enterprise version allows internal, proprietary data to be uploaded and integrated into the NextBio database of publicly-available data. According to the company, scientists are using NextBio to improve their ability to identify relevant prognostic and predictive molecular signatures which are significant in their research.
NextBio was a receiver of the Frost & Sullivan
North American Life Sciences Customer Value Enhancement Award in 2008.
Mostafa Ronaghi
Mostafa Ronaghi, born 1968. is a molecular biologist, specializing in DNA sequencing methodology . He earned his Ph.D. from the Royal Institute of Technology in Sweden in 1998.He is currently the Chief Technology Officer and Senior Vice President at Illumina...
in 2004 and based in Cupertino, California
Cupertino, California
Cupertino is an affluent suburban city in Santa Clara County, California in the U.S., directly west of San Jose on the western edge of the Santa Clara Valley with portions extending into the foothills of the Santa Cruz Mountains. The population was 58,302 at the time of the 2010 census. Forbes...
, USA.
The NextBio Platform is an ontology
Ontology
Ontology is the philosophical study of the nature of being, existence or reality as such, as well as the basic categories of being and their relations...
-based semantic framework that connects highly heterogeneous data and textual information. The semantic framework is based on gene, tissue, disease and compound ontologies. This framework contains information from different organisms, platforms, data types and research areas that is integrated into and correlated within a single searchable environment using proprietary algorithms. It provides a unified interface for researchers to formulate and test new hypotheses across vast collections of experimental data.
According to the company, the enterprise version of the NextBio platform is being used in life science research and development and drug development by researchers and clinicians at: Merck Pharmaceutical
Merck & Co.
Merck & Co., Inc. , also known as Merck Sharp & Dohme or MSD outside the United States and Canada, is one of the largest pharmaceutical companies in the world. The Merck headquarters is located in Whitehouse Station, New Jersey, an unincorporated area in Readington Township...
, Johnson & Johnson
Johnson & Johnson
Johnson & Johnson is an American multinational pharmaceutical, medical devices and consumer packaged goods manufacturer founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500....
Pharmaceutical Research & Development, L.L.C., Celgene
Celgene
Celgene Corporation is a manufacturer of drug therapies for cancer and inflammatory disorders. It is incorporated in Delaware and headquartered in Summit, New Jersey...
, Genzyme
Genzyme
Genzyme Corporation is a fully owned subsidiary of Sanofi-Aventis. Before its acquisition, Genzyme was an American biotechnology company based in Cambridge, Massachusetts. In 2010, Genzyme was the world’s third-largest biotechnology company, employing more than 11,000 people around the world...
, Eli Lilly and Company
Eli Lilly and Company
Eli Lilly and Company is a global pharmaceutical company. Eli Lilly's global headquarters is located in Indianapolis, Indiana, in the United States...
, and Regeneron Pharmaceuticals. This enterprise version allows internal, proprietary data to be uploaded and integrated into the NextBio database of publicly-available data. According to the company, scientists are using NextBio to improve their ability to identify relevant prognostic and predictive molecular signatures which are significant in their research.
NextBio was a receiver of the Frost & Sullivan
Frost & Sullivan
Frost & Sullivan, Inc. is an American firm which provides market research & analysis, growth strategy consulting and corporate training services. Its headquarters are located in San Antonio, Texas, with offices in over 20 countries across the world....
North American Life Sciences Customer Value Enhancement Award in 2008.