Nodular fasciitis
Encyclopedia
Nodular fasciitis, also known as nodular pseudosarcomatous fasciits, pseudosarcomatous fasciitis, and subcutaneous pseudosarcomatous fibromatosis, is a benign
soft tissue
lesion
most commonly found in the superficial
fascia
. It is most common in young persons on the upper extremities and trunk, and typically associated with previous injury
at the site. It may be mistaken for a sarcoma
.
, it is believed to be a reparative process secondary to trauma
, which is frequently not remembered. It evolves rapidly, but is usually less than 3 cm in diameter. There is an extremely low incidence of recurrence after resection.
Benign
A benign tumor is a tumor that lacks the ability to metastasize. Common examples of benign tumors include moles and uterine fibroids.The term "benign" implies a mild and nonprogressive disease. Indeed, many kinds of benign tumors are harmless to human health...
soft tissue
Soft tissue
In anatomy, the term soft tissue refers to tissues that connect, support, or surround other structures and organs of the body, not being bone. Soft tissue includes tendons, ligaments, fascia, skin, fibrous tissues, fat, and synovial membranes , and muscles, nerves and blood vessels .It is sometimes...
lesion
Lesion
A lesion is any abnormality in the tissue of an organism , usually caused by disease or trauma. Lesion is derived from the Latin word laesio which means injury.- Types :...
most commonly found in the superficial
Superficial
Superficial may refer to:*Superficial , an album by Heidi Montag*"Superficial" *The Superficial, a website devoted to celebrity gossip...
fascia
Fascia
A fascia is a layer of fibrous tissue that permeates the human body. A fascia is a connective tissue that surrounds muscles, groups of muscles, blood vessels, and nerves, binding those structures together in much the same manner as plastic wrap can be used to hold the contents of sandwiches...
. It is most common in young persons on the upper extremities and trunk, and typically associated with previous injury
Injury
-By cause:*Traumatic injury, a body wound or shock produced by sudden physical injury, as from violence or accident*Other injuries from external physical causes, such as radiation injury, burn injury or frostbite*Injury from infection...
at the site. It may be mistaken for a sarcoma
Sarcoma
A sarcoma is a cancer that arises from transformed cells in one of a number of tissues that develop from embryonic mesoderm. Thus, sarcomas include tumors of bone, cartilage, fat, muscle, vascular, and hematopoietic tissues...
.
Etiology and clinical course
Similar to a dermatofibromaDermatofibroma
Benign fibrous histiocytomas are benign skin growths.-Presentation:...
, it is believed to be a reparative process secondary to trauma
Trauma
Trauma can refer to:-In psychology and medicine:* Trauma , an often serious and body-altering physical injury, such as the removal of a limb...
, which is frequently not remembered. It evolves rapidly, but is usually less than 3 cm in diameter. There is an extremely low incidence of recurrence after resection.
Histology
- Histologically vast array of patterns.
- Short S-shaped fascicles, inflammation, accelerated mitotic indexMitotic indexMitotic index is a measure for the proliferation status of a cell population. It is defined as the ratio between the number of cells in mitosis and the total number of cells....
with normal mitoses. - Essentially spindle cell proliferation.
- Stroma is rich in collagen and/or myxoid ground substance.
See also
- LeiomyosarcomaLeiomyosarcomaLeiomyosarcoma , aka LMS, is a malignant cancer of smooth muscle....
- List of cutaneous conditions
- Inflammatory myofibroblastic tumourInflammatory myofibroblastic tumourInflammatory myofibroblastic tumour, also known as inflammatory pseudotumour and inflammatory fibrosarcoma, is a soft tissue lesion that may be confused with a sarcoma...