Non-X histiocytosis
Encyclopedia
Non-X histiocytoses are a clinically well-defined group of cutaneous syndromes characterized by infiltrates of monocytes/macrophages, as opposed to X-type histiocytoses in which the infiltrates contain Langerhans cell
s. Conditions included in this group are:
Langerhans cell
Langerhans cells are dendritic cells of the skin and mucosa, and contain large granules called Birbeck granules. They are present in all layers of the epidermis, but are most prominant in the stratum spinosum. They also occur in the papillary dermis, particularly around blood vessels, as well as...
s. Conditions included in this group are:
- Juvenile xanthogranulomaJuvenile xanthogranulomaJuvenile xanthogranuloma is a form of histiocytosis, classified as "non-Langerhans cell histiocytosis", or more specifically, "type 2"....
- Benign cephalic histiocytosisBenign cephalic histiocytosisBenign cephalic histiocytosis is a rare cutaneous condition affecting boys and girls equally, characterized by skin lesions that initially present on the head in all cases, often the cheeks, eyelids, forehead, and ears....
- Generalized eruptive histiocytomaGeneralized eruptive histiocytomaGeneralized eruptive histiocytoma is a rare cutaneous condition characterized by widespread, erythematous, essentially symmetrical papules, particularly involving the trunk and proximal extremities....
- Xanthoma disseminatumXanthoma disseminatumXanthoma disseminatum is a rare cutaneous condition that preferentially affects males in childhood, characterized by the insidious onset of small, yellow-red to brown papules and nodules that are discrete and disseminated.It is a histiocytosis syndrome.- References :...
- Progressive nodular histiocytosisProgressive nodular histiocytosisProgressive nodular histiocytosis is a cutaneous condition clinically characterized by the development of two types of skin lesions: superficial papules and deeper larger subcutaneous nodules....
- Papular xanthomaPapular xanthomaPapular xanthoma is a cutaneous condition that is a rare form of non-X histiocytosis....
- Hereditary progressive mucinous histiocytosisHereditary progressive mucinous histiocytosisHereditary progressive mucinous histiocytosis is an autosomal dominant or X-linked hereditary described on in women....
- ReticulohistiocytosisReticulohistiocytosisReticulohistiocytosis is a cutaneous condition of which there are two distinct forms:* Reticulohistiocytoma* Multicentric reticulohistiocytosis...
- Indeterminate cell histiocytosisIndeterminate cell histiocytosisIndeterminate cell histiocytosis is a cutaneous condition felt to be caused by dermal precursors of Langerhans cells....
- Sea-blue histiocytosisSea-blue histiocytosisSea-blue histiocytosis is a cutaneous condition that may occur as a familial inherited syndrome or as an acquired secondary or systemic infiltrative process.-Causes:It can be associated with the gene APOE.It can also be acquired...