Non-histone protein
Encyclopedia
In chromatin
, those proteins which remain after the histones have been removed, are classified as non-histone proteins. Scaffold proteins
, DNA polymerase
, Heterochromatin Protein 1
and Polycomb
are common non-histone proteins. This classification group also includes numerous other structural, regulatory, and motor proteins.
Chromatin
Chromatin is the combination of DNA and proteins that make up the contents of the nucleus of a cell. The primary functions of chromatin are; to package DNA into a smaller volume to fit in the cell, to strengthen the DNA to allow mitosis and meiosis and prevent DNA damage, and to control gene...
, those proteins which remain after the histones have been removed, are classified as non-histone proteins. Scaffold proteins
Scaffold protein
In biology, scaffold proteins are crucial regulators of many key signaling pathways. Although scaffolds are not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes...
, DNA polymerase
DNA polymerase
A DNA polymerase is an enzyme that helps catalyze in the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are best known for their feedback role in DNA replication, in which the polymerase "reads" an intact DNA strand as a template and uses it to synthesize the new strand....
, Heterochromatin Protein 1
Heterochromatin protein 1
The family of Heterochromatin Protein 1 are highly conserved adapter proteins, which have important functions in the cell nucleus...
and Polycomb
Polycomb-group proteins
Polycomb-group proteins are a family of proteins first discovered in fruit flies that can remodel chromatin such that epigenetic silencing of genes takes place...
are common non-histone proteins. This classification group also includes numerous other structural, regulatory, and motor proteins.