Null cell
Encyclopedia
A null cell is a large granular lymphocyte
without surface markers or membrane-associated proteins from B lymphocytes or T lymphocytes. Natural killer cell
s are usually null cells with surface marker CD 16 which bind to the Fc portion of the IgG, and thereby destroy it. NK-cells do immune surveillance, attack pathogens and abnormal cells. members of null cells are NK cells, antigen dependent cytotoxic cells(ADCC), and the lymphokine activated killer(LAK)cells.
In 75% of the cases of ALL, the lymphocytes are neither B nor T-cells and are called Null cells.
Lymphocyte
A lymphocyte is a type of white blood cell in the vertebrate immune system.Under the microscope, lymphocytes can be divided into large lymphocytes and small lymphocytes. Large granular lymphocytes include natural killer cells...
without surface markers or membrane-associated proteins from B lymphocytes or T lymphocytes. Natural killer cell
Natural killer cell
Natural killer cells are a type of cytotoxic lymphocyte that constitute a major component of the innate immune system. NK cells play a major role in the rejection of tumors and cells infected by viruses...
s are usually null cells with surface marker CD 16 which bind to the Fc portion of the IgG, and thereby destroy it. NK-cells do immune surveillance, attack pathogens and abnormal cells. members of null cells are NK cells, antigen dependent cytotoxic cells(ADCC), and the lymphokine activated killer(LAK)cells.
In 75% of the cases of ALL, the lymphocytes are neither B nor T-cells and are called Null cells.