State Route 255 is an east–west state route located in southeast Ohio

Ohio

Ohio is a Midwestern state in the United States. The 34th largest state by area in the U.S.,it is the 7th‑most populous with over 11.5 million residents, containing several major American cities and seven metropolitan areas with populations of 500,000 or more.The state's capital is Columbus...

. Nestled entirely inside the southeast quadrant of Monroe County

Monroe County, Ohio

Monroe County is a county located in the state of Ohio. As of the 2010 census, the population was 14,642. Its county seat is Woodsfield and is named for James Monroe, Secretary of State when the county was formed and later President of the United States....

, the western terminus of State Route 255 is at a T-intersection with State Route 800

Ohio State Route 800

State Route 800 is a north–south state highway in the eastern portion of the U.S. state of Ohio. Its southern terminus is at State Route 7 near New Matamoras, and its northern terminus is at its interchange with Interstate 77 in Canton....

 approximately 3 miles (4.8 km) south of Woodsfield

Woodsfield, Ohio

Woodsfield is a village in Monroe County, Ohio, United States. The population was 2,598 at the 2000 census. It is the county seat of Monroe County and houses the Monroe County Courthouse.-Geography:Woodsfield is located at ....

. Its eastern terminus is at State Route 7 in the hamlet of Sardis

Sardis, Ohio

Sardis is an unincorporated community in southeastern Lee Township, Monroe County, Ohio, United States. Although it is unincorporated, it has a post office with the ZIP code of 43946...

, which is situated along the banks of the Ohio River

Ohio River

The Ohio River is the largest tributary, by volume, of the Mississippi River. At the confluence, the Ohio is even bigger than the Mississippi and, thus, is hydrologically the main stream of the whole river system, including the Allegheny River further upstream...

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Major intersections