The second generation was launched in 2001. While most competitors severed their connections with their subcompact brethren, Opel decided to base the vehicle on the Corsa again. The use of subcompact Gamma platform

GM Gamma platform

Gamma is General Motors' and Fiat's global subcompact front-wheel drive automobile platform.-GM4300:The first version of the platform was issued in autumn 2000 with the introduction of Opel Corsa C and was a development of the earlier GM4200 platform used in previous Corsa models, developed by Opel...

 constrained the overall width of the vehicle. While the general body shape was updated to fashionable "flush" look, the front part (up to the A-pillar) is shared with the Corsa. Compared to previous generation, the Combo B gained sliding rear side doors (versions with either single passenger side door or double doors are available).
An Opel Combo Tour version was also introduced, followed by Opel Combo Tour Tramp (Combo Tour Arizona in some markets), in an attempt to attract leisure activity vehicle

Leisure activity vehicle

A leisure activity vehicle is a small van, generally related to a supermini or subcompact car, with two or three seat rows, and a large, tall car boot and tailgate. An early example of the category was the Matra Rancho introduced in 1977...

 buyers.