Opequon Creek is a 64.4 miles (103.6 km) tributary

Tributary

A tributary or affluent is a stream or river that flows into a main stem river or a lake. A tributary does not flow directly into a sea or ocean...

 stream

Stream

A stream is a body of water with a current, confined within a bed and stream banks. Depending on its locale or certain characteristics, a stream may be referred to as a branch, brook, beck, burn, creek, "crick", gill , kill, lick, rill, river, syke, bayou, rivulet, streamage, wash, run or...

 of the Potomac River

Potomac River

The Potomac River flows into the Chesapeake Bay, located along the mid-Atlantic coast of the United States. The river is approximately long, with a drainage area of about 14,700 square miles...

. It flows into the Potomac northeast of Martinsburg

Martinsburg, West Virginia

Martinsburg is a city in the Eastern Panhandle region of West Virginia, United States. The city's population was 14,972 at the 2000 census; according to a 2009 Census Bureau estimate, Martinsburg's population was 17,117, making it the largest city in the Eastern Panhandle and the eighth largest...

 in Berkeley County

Berkeley County, West Virginia

Berkeley County is a county located in the Eastern Panhandle region of the U.S. state of West Virginia. As of 2010, the population is 104,169, making it the second-most populous county in West Virginia, behind Kanawha...

, West Virginia

West Virginia

West Virginia is a state in the Appalachian and Southeastern regions of the United States, bordered by Virginia to the southeast, Kentucky to the southwest, Ohio to the northwest, Pennsylvania to the northeast and Maryland to the east...

, and its source lies northwest of the community of Opequon

Opequon, Virginia

Opequon is an unincorporated community along Opequon Creek in Frederick County, Virginia. Opequon is located on Cedar Creek Grade at Miller Road and also known as Kernstown, Virginia. The community of Opequon was designated a National Historic District in 2002. Opequon School, which was in...

 at the foot of Great North Mountain

Great North Mountain

Great North Mountain is a long mountain range within the Ridge-and-valley Appalachians in the U.S. states of Virginia and West Virginia. The range is located west of the Shenandoah Valley and Massanutten Mountain in Virginia, and east of the Allegheny Mountains and Cacapon River in West...

 in Frederick County

Frederick County, Virginia

Frederick County is a county located in the Commonwealth of Virginia. It is included in the Winchester, Virginia-West Virginia Metropolitan Statistical Area. It was formed in 1743 by the splitting of Orange County. For ten years it was the home of George Washington. As of 2010, the population was...

, Virginia

Virginia

The Commonwealth of Virginia , is a U.S. state on the Atlantic Coast of the Southern United States. Virginia is nicknamed the "Old Dominion" and sometimes the "Mother of Presidents" after the eight U.S. presidents born there...

. The Opequon forms part of the boundary between Frederick and Clarke

Clarke County, Virginia

Clarke County is a county in the Commonwealth of Virginia. As of 2010, the population was 14,034. Its county seat is Berryville.-History:Clarke County was established in 1836 by Thomas Fairfax, 6th Lord Fairfax of Cameron who built a home, Greenway Court, on part of his 5 million acre property,...

 counties in Virginia and also partially forms the boundary between Berkeley and Jefferson

Jefferson County, West Virginia

Jefferson County is a county located in the U.S. state of West Virginia. As of 2010, the population was 53,498. Its county seat is Charles Town...

 counties in West Virginia's Eastern Panhandle

Eastern Panhandle of West Virginia

The Eastern Panhandle of West Virginia is a narrow stretch of territory in the northeast of the state, bordering Maryland and Virginia, United States. The Eastern Panhandle Board of Realtors and other local civic organizations consider only the three Easternmost counties, Jefferson, Berkeley and...

.

Tributaries

Streams are listed from south (headwaters) to the north (mouth).

• Stribling Run
• Hoge Run
• Wrights Run
• Buffalo Lick Run
• Sulphur Spring Run
• Isaac Run
• Abrams Creek
  Abrams Creek
  Abrams Creek is an tributary stream of Opequon Creek in Frederick County and the independent city of Winchester in Virginia. Abrams Creek rises north of Round Hill and flows in a southeasterly direction through Winchester. From Winchester, Abrams Creek flows east into Opequon Creek...
  
  
  • Town Run
  • Ash Hollow Run
• Redbud Run
• Dry Marsh Run
• Lick Run
• Littlers Run
  • Ross Run
• Thomas Run
• Abrils Run
• Duncan Run
• Silver Spring Run
• Specks Run
• Turkey Run
• Mill Creek
  Mill Creek (Opequon Creek)
  Mill Creek is a tributary of Opequon Creek, belonging to the Potomac River and Chesapeake Bay watersheds, located in Berkeley County in West Virginia's Eastern Panhandle...
  
  
  • Torytown Run
  • Sylvan Run
• Three Run
• Goose Creek
• Middle Creek
  Middle Creek (Opequon Creek)
  Middle Creek is a tributary of Opequon Creek, belonging to the Potomac River and Chesapeake Bay watersheds, located in Berkeley County in West Virginia's Eastern Panhandle.-Headwaters and course:...
  
  
• Hopewell Run
  • Dry Run
• Buzzard Run
• Sulphur Spring Branch
• Spa Run
• Cold Spring Run
• Evens Run
• Tuscarora Creek
  Tuscarora Creek (Opequon Creek)
  Tuscarora Creek is an tributary of Opequon Creek, belonging to the Potomac River and Chesapeake Bay watersheds, located in Berkeley County in West Virginia's Eastern Panhandle. Tuscarora Creek flows through the city of Martinsburg. Tuscarora Creek rises on the eastern flanks of North Mountain....
  
  
• Eagle Run
• Hoke Run

List of cities and towns along Opequon Creek

• Baker Heights
  Baker Heights, West Virginia
  Baker Heights is an unincorporated community near Opequon Creek in Berkeley County in the U.S. state of West Virginia. Located on West Virginia Route 9 southeast of Martinsburg, Baker Heights is the site of the Martinsburg Veterans Affairs Medical Center....
  
  
• Bartonsville
  Bartonsville, Virginia
  Bartonsville is an unincorporated community located along Opequon Creek in Frederick County, Virginia between Winchester and Stephens City. Bartonsville is on Springdale Road to the west of Valley Pike...
  
  
• Bedington
  Bedington, West Virginia
  Bedington is an unincorporated hamlet on Hoke Run, near its confluence with Opequon Creek, in Berkeley County, West Virginia. It is located east of Hainesville on County Route 5. According to the Geographic Names Information System, Bedington has also been known as Beddington, Bedenton, and The Lick....
  
  
• Blairton
  Blairton, West Virginia
  Blairton is an unincorporated community on Opequon Creek located east of Martinsburg in Berkeley County, West Virginia. Blairton was originally named Opequan Station because of its location on the Opequon along the railroad....
  
  
• Burnt Factory
  Burnt Factory, Virginia
  Burnt Factory is an unincorporated community in Frederick County, Virginia, USA. Burnt Factory lies to the northeast of Winchester along Opequon Creek. The community is centered at the intersection of Burnt Factory and Jordan Springs Roads....
  
  
• Leetown
  Leetown, Virginia
  Leetown is an unincorporated town in northern Frederick County, Virginia, USA. Leetown is located on Old Charles Town Road at its intersection with Gun Club Road to the west of Opequon Creek. According to the Geographic Names Information System, Leetown has also been known throughout its history...
  
  
• Martinsburg
  Martinsburg, West Virginia
  Martinsburg is a city in the Eastern Panhandle region of West Virginia, United States. The city's population was 14,972 at the 2000 census; according to a 2009 Census Bureau estimate, Martinsburg's population was 17,117, making it the largest city in the Eastern Panhandle and the eighth largest...
  
  
• Middleway
  Middleway, West Virginia
  Middleway is an unincorporated census-designated place in Jefferson County, West Virginia, USA. As of the 2010 census, its population was 441.-History:...
  
  
• Opequon
  Opequon, Virginia
  Opequon is an unincorporated community along Opequon Creek in Frederick County, Virginia. Opequon is located on Cedar Creek Grade at Miller Road and also known as Kernstown, Virginia. The community of Opequon was designated a National Historic District in 2002. Opequon School, which was in...
  
  
• Parkins Mills
  Parkins Mills, Virginia
  Parkins Mills is an unincorporated community in Frederick County, Virginia. Parkins Mills lies southeast of Winchester on the Front Royal Pike at Opequon Creek....
  
  
• Tarico Heights
  Tarico Heights, West Virginia
  Tarico Heights is an unincorporated community on West Virginia Route 51 along Opequon Creek in Berkeley County, West Virginia....
  
  
• Wadesville
  Wadesville, Virginia
  Wadesville is an unincorporated community in Clarke County in the U.S. state of Virginia. Wadesville is located along Opequon Creek....
  
  
• Inwood
  Inwood, West Virginia
  Inwood is a census-designated place in Berkeley County, West Virginia, United States, located south of Martinsburg. The population was 2,954 at the 2010 census. It is located on U.S...