OrbusNeich
Encyclopedia
OrbusNeich is a global company that designs, develops, manufactures and markets medical devices for the treatment of vascular diseases.
OrbusNeich is well known for the development of Genous, the endothelial progenitor cell
(EPC) capture technology that promotes the accelerated natural healing of the vessel wall after the implantation of blood-contact devices such as stents. The technology consists of an antibody
surface coating that attracts EPCs circulating in the blood
to the device to form an endothelial layer that provides protection against thrombosis
and modulates restenosis
.
Orbus Medical Technologies was founded in 1996. Orbus began as a medical device company and developed the R stent, a bare-metal stent
with a novel dual helix design. With the development of the Genous EPC capture technology in 2001, the company created the world’s first pro-healing stent, the Genous Bio-engineered Stent.
Neich International was incorporated in Hong Kong in 1979 as the sole distributor for Cordis
in the Asia-Pacific region, including Japan. Neich’s operations and sales were absorbed into Johnson & Johnson
with their acquisition of Cordis
in 1996. In 1999, Neich Medical re-entered interventional cardiology
with investments in and agreements with Orbus Medical Technologies. 2001 saw the opening of manufacturing facility in Shenzhen, China.
OrbusNeich is well known for the development of Genous, the endothelial progenitor cell
Endothelial progenitor cell
Endothelial progenitor cells are a population of rare cells that circulate in the blood with the ability to differentiate into endothelial cells, the cells that make up the lining of blood vessels. The process by which blood vessels are born de novo from endothelial progenitor cells is known as...
(EPC) capture technology that promotes the accelerated natural healing of the vessel wall after the implantation of blood-contact devices such as stents. The technology consists of an antibody
Antibody
An antibody, also known as an immunoglobulin, is a large Y-shaped protein used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The antibody recognizes a unique part of the foreign target, termed an antigen...
surface coating that attracts EPCs circulating in the blood
Blood
Blood is a specialized bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells....
to the device to form an endothelial layer that provides protection against thrombosis
Thrombosis
Thrombosis is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel is injured, the body uses platelets and fibrin to form a blood clot to prevent blood loss...
and modulates restenosis
Restenosis
Restenosis literally means the reoccurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow. Restenosis usually pertains to an artery or other large blood vessel that has become narrowed, received treatment to clear the blockage and subsequently become renarrowed...
.
Brief History
OrbusNeich was founded in 2005, the result of a merger between Orbus Medical Technologies of Fort Lauderdale, Florida, and Hong Kong-headquartered Neich Medical.Orbus Medical Technologies was founded in 1996. Orbus began as a medical device company and developed the R stent, a bare-metal stent
Bare-metal stent
Bare-metal stent is a vascular stent without a coating . It is a mesh-like tube of thin wire. The first stents licenced for use in cardiac arteries were bare metal - often 316L stainless steel...
with a novel dual helix design. With the development of the Genous EPC capture technology in 2001, the company created the world’s first pro-healing stent, the Genous Bio-engineered Stent.
Neich International was incorporated in Hong Kong in 1979 as the sole distributor for Cordis
Cordis (medical)
Cordis is a medical device company owned by Johnson & Johnson. The company was founded in Miami in 1959 and is currently headquartered in Bridgewater Township, New Jersey.Cordis' products include stents, distal protection devices, catheters, and guidewires....
in the Asia-Pacific region, including Japan. Neich’s operations and sales were absorbed into Johnson & Johnson
Johnson & Johnson
Johnson & Johnson is an American multinational pharmaceutical, medical devices and consumer packaged goods manufacturer founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500....
with their acquisition of Cordis
Cordis (medical)
Cordis is a medical device company owned by Johnson & Johnson. The company was founded in Miami in 1959 and is currently headquartered in Bridgewater Township, New Jersey.Cordis' products include stents, distal protection devices, catheters, and guidewires....
in 1996. In 1999, Neich Medical re-entered interventional cardiology
Interventional cardiology
Interventional cardiology is a branch of cardiology that deals specifically with the catheter based treatment of structural heart diseases. Andreas Gruentzig is considered the father of interventional cardiology after the development of angioplasty by interventional radiologist, Dr. Charles...
with investments in and agreements with Orbus Medical Technologies. 2001 saw the opening of manufacturing facility in Shenzhen, China.