Oxypurinol
Encyclopedia
Oxypurinol is an inhibitor of xanthine oxidase
. It is an active metabolite of allopurinol
and it is cleared renally. In cases of renal disease, this metabolite will accumulate to toxic levels.
Xanthine oxidase
Xanthine oxidase Xanthine oxidase Xanthine oxidase (XO (sometimes 'XAO'), a form of xanthine oxidoreductase that generates reactive oxygen species. Is an enzyme that catalyzes the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid...
. It is an active metabolite of allopurinol
Allopurinol
Allopurinol is a drug used primarily to treat hyperuricemia and its complications, including chronic gout.- Mechanism of action :...
and it is cleared renally. In cases of renal disease, this metabolite will accumulate to toxic levels.