PICK1
Encyclopedia
PRKCA-binding protein is a protein
that in humans is encoded by the PICK1 gene
.
with HER2/neu
, ACCN2
, Metabotropic glutamate receptor 7
, BNC1
, Metabotropic glutamate receptor 3
, GRIA4
, Dopamine transporter
, GRIK1
, GRIK2
, GRIK3
, GRIA2
and GRIA3
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the PICK1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
PICK1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with HER2/neu
HER2/neu
HER-2 also known as proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, CD340 or p185 is an enzyme that in humans is encoded by the ERBB2 gene. Over expression of this gene is correlated with higher aggressiveness in breast cancers...
, ACCN2
ACCN2
Amiloride-sensitive cation channel 2, neuronal is a protein that in humans is encoded by the ACCN2 gene.- Function :This gene encodes a member of the degenerin/epithelial sodium channel superfamily...
, Metabotropic glutamate receptor 7
Metabotropic glutamate receptor 7
Metabotropic glutamate receptor 7 is a protein that in humans is encoded by the GRM7 gene.-Agonists:*AMN082: allosteric agonist; induces rapid internalization; non-glutamatergic binding component-Interactions:...
, BNC1
BNC1
Zinc finger protein basonuclin-1 is a protein that in humans is encoded by the BNC1 gene.-Further reading:...
, Metabotropic glutamate receptor 3
Metabotropic glutamate receptor 3
Metabotropic glutamate receptor 3 is a protein that in humans is encoded by the GRM3 gene.-Ligands:Though truly mGluR3 selective agents still await their discovery, mixed mGluR2/3 ligands with selectivity over other mGluR-subtypes are known...
, GRIA4
GRIA4
Glutamate receptor 4 is a protein that in humans is encoded by the GRIA4 gene.-Interactions:GRIA4 has been shown to interact with CACNG2, GRIP1, PICK1 and PRKCG.-RNA editing:...
, Dopamine transporter
Dopamine transporter
The dopamine transporter is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synapse back into cytosol, from which other transporters sequester DA and NE into vesicles for later storage and release...
, GRIK1
GRIK1
Glutamate receptor, ionotropic, kainate 1, also known as GRIK1, is a protein that in humans is encoded by the GRIK1 gene.- Function :...
, GRIK2
GRIK2
Glutamate receptor, ionotropic kainate 2 is a protein that in humans is encoded by the GRIK2 gene.- Clinical significance :Homozygosity for a GRIK2 deletion-inversion mutation is associated with nonsyndromic autosomal recessive mental retardation....
, GRIK3
GRIK3
Glutamate receptor, ionotropic kainate 3 is a protein that in humans is encoded by the GRIK3 gene....
, GRIA2
GRIA2
Glutamate receptor 2 is a protein that in humans is encoded by the GRIA2 gene.- Function :Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes...
and GRIA3
GRIA3
Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene.- Function :Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes...
.