PLEXION
Encyclopedia
The drug combination sulfacetamide/sulfur is a topical
acne
medication
manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar. It combines sodium sulfacetamide
, a sulfonamide
antibiotic
, and sulfur
, a keratolytic
agent. It is available in four formulations
: as a cleansing cloth
, cleanser
, topical suspension
, and as a facial mask. The sulfacetamide inhibits the growth of the bacterium Propionibacterium acnes
that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores.
Topical
In medicine, a topical medication is applied to body surfaces such as the skin or mucous membranes such as the vagina, anus, throat, eyes and ears.Many topical medications are epicutaneous, meaning that they are applied directly to the skin...
acne
Acne
Acne is a general term used for acneiform eruptions. It is usually used as a synonym for acne vulgaris, but may also refer to:*Acne aestivalis*Acne conglobata*Acne cosmetica*Acne fulminans*Acne keloidalis nuchae*Acne mechanica...
medication
Medication
A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease.- Classification :...
manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar. It combines sodium sulfacetamide
Sulfacetamide
Sulfacetamide is a sulfonamide antibiotic.-Uses:Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. When combined with sulfur, it is sold under the brand names Plexion, Clenia, Prascion, and Avar, which...
, a sulfonamide
Sulfonamide (medicine)
Sulfonamide or sulphonamide is the basis of several groups of drugs. The original antibacterial sulfonamides are synthetic antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of antibacterial activity, e.g., the anticonvulsant sultiame...
antibiotic
Antibiotic
An antibacterial is a compound or substance that kills or slows down the growth of bacteria.The term is often used synonymously with the term antibiotic; today, however, with increased knowledge of the causative agents of various infectious diseases, antibiotic has come to denote a broader range of...
, and sulfur
Sulfur
Sulfur or sulphur is the chemical element with atomic number 16. In the periodic table it is represented by the symbol S. It is an abundant, multivalent non-metal. Under normal conditions, sulfur atoms form cyclic octatomic molecules with chemical formula S8. Elemental sulfur is a bright yellow...
, a keratolytic
Keratolytic
Keratolytic therapy is treatment to remove warts and other lesions in which the epidermis produces excess skin. In this therapy, acid medicine, such as salicylic acid is put on the lesion. Keratolytic therapy thins the skin on and around the lesion. It causes the outer layer of the skin to loosen...
agent. It is available in four formulations
Pharmaceutical formulation
Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product.-Stages and timeline:...
: as a cleansing cloth
Wet wipe
A wet wipe, also known as a wet nap, wet towel, or a moist towelette, is a small moistened piece of paper or cloth that often comes folded and individually wrapped for convenience...
, cleanser
Cleanser
A cleanser is a product used to cleanse something, such as a detergent or industrial cleaning agent.A popular type of cleanser is a facial care product that is used to remove make-up, dead skin cells, oil, dirt, and other types of pollutants from the skin of the face...
, topical suspension
Suspension (chemistry)
In chemistry, a suspension is a heterogeneous fluid containing solid particles that are sufficiently large for sedimentation. Usually they must be larger than 1 micrometer. The internal phase is dispersed throughout the external phase through mechanical agitation, with the use of certain...
, and as a facial mask. The sulfacetamide inhibits the growth of the bacterium Propionibacterium acnes
Propionibacterium acnes
Propionibacterium acnes is a relatively slow growing, typically aerotolerant anaerobic gram positive bacterium that is linked to the skin condition acne; it can also cause chronic blepharitis and endophthalmitis, the latter particularly following intraocular surgery...
that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores.