PPM1B
Encyclopedia
Protein phosphatase 1B is an enzyme
that in humans is encoded by the PPM1B gene
.
with IKBKG
, IKK2
, Cyclin-dependent kinase 2
, Cyclin-dependent kinase 6
, CHUK
and MAP3K7
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the PPM1B gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
PPM1B has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with IKBKG
IKBKG
NF-kappa-B essential modulator also known as inhibitor of nuclear factor kappa-B kinase subunit gamma is a protein that in humans is encoded by the IKBKG gene. NEMO is a subunit of the IκB kinase that activates NF-κB. The human gene for IKBKG is located on chromosome Xq28...
, IKK2
IKK2
IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB gene.- Function :...
, Cyclin-dependent kinase 2
Cyclin-dependent kinase 2
Cyclin-dependent kinase 2 also known as cell division protein kinase 2 is an enzyme that in humans is encoded by the CDK2 gene.-Function:...
, Cyclin-dependent kinase 6
Cyclin-dependent kinase 6
Cell division protein kinase 6 is an enzyme that in humans is encoded by the CDK6 gene.It is regulated by Cyclin D.-Interactions:Cyclin-dependent kinase 6 has been shown to interact with CDKN2C, P16, PPM1B, Cyclin D3, Cyclin D1 and PPP2CA....
, CHUK
CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha also known as IKK1 or conserved helix-loop-helix ubiquitous kinase is a protein kinase that in humans is encoded by the CHUK gene. IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription...
and MAP3K7
MAP3K7
Mitogen-activated protein kinase kinase kinase 7 is an enzyme that in humans is encoded by the MAP3K7 gene.-Interactions:MAP3K7 has been shown to interact with Mothers against decapentaplegic homolog 6, MAP3K7IP2, MAP3K7IP1, MAP3K7IP3, ASK1, PPM1B, TRAF6, MAP2K6 and CHUK.-Further reading:...
.