PRKAR2A
Encyclopedia
cAMP-dependent protein kinase type II-alpha regulatory subunit is an enzyme
that in humans is encoded by the PRKAR2A gene
.
with AKAP2
, AKAP1
, AKAP11
, AKAP8
, ARFGEF2
, AKAP9
, GSK3B
, AKAP3
, RUNX1T1
, AKAP13
, CBFA2T3
and PDE4A
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the PRKAR2A gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
PRKAR2A has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with AKAP2
AKAP2
A-kinase anchor protein 2 is an enzyme that in humans is encoded by the AKAP2 gene.-Further reading:...
, AKAP1
AKAP1
A kinase anchor protein 1, mitochondrial is an enzyme that in humans is encoded by the AKAP1 gene.-Interactions:AKAP1 has been shown to interact with MYCBP, C3orf15, PRKAR1A, PRKAR2A and PRKAR1B.-Further reading:...
, AKAP11
AKAP11
A-kinase anchor protein 11 is an enzyme that in humans is encoded by the AKAP11 gene.-Interactions:AKAP11 has been shown to interact with PPP1CA, GSK3B, PRKAR2A and PRKAR2B.-Further reading:...
, AKAP8
AKAP8
A-kinase anchor protein 8 is an enzyme that in humans is encoded by the AKAP8 gene.-Interactions:AKAP8 has been shown to interact with DDX5, AMY1A, MCM2, Cyclin D3 and PRKAR2A.-Further reading:...
, ARFGEF2
ARFGEF2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 is a protein that in humans is encoded by the ARFGEF2 gene.-Interactions:ARFGEF2 has been shown to interact with ARFGEF1, PRKAR1A and PRKAR2A.-Further reading:...
, AKAP9
AKAP9
A-kinase anchor protein 9 is an enzyme that in humans is encoded by the AKAP9 gene.-Interactions:AKAP9 has been shown to interact with Calmodulin 1, FNBP1, CALM2, Protein kinase N1, TRIP10, KvLQT1 and PRKAR2A.-Further reading:...
, GSK3B
GSK3B
Glycogen synthase kinase 3 beta, also known as GSK3B, is an enzyme that in humans is encoded by the GSK3B gene.- Function :Glycogen synthase kinase-3 is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms,...
, AKAP3
AKAP3
A-kinase anchor protein 3 is an enzyme that in humans is encoded by the AKAP3 gene.-Interactions:AKAP3 has been shown to interact with GNA13, AKAP4 and PRKAR2A.-Further reading:...
, RUNX1T1
RUNX1T1
Protein CBFA2T1 is a protein that in humans is encoded by the RUNX1T1 gene.-Interactions:RUNX1T1 has been shown to interact with CBFA2T2, Zinc finger and BTB domain-containing protein 16, Nuclear receptor co-repressor 1, Nuclear receptor co-repressor 2, CBFA2T3, GFI1, Calcitriol receptor and...
, AKAP13
AKAP13
A-kinase anchor protein 13 is an enzyme that in humans is encoded by the AKAP13 gene.-Interactions:AKAP13 has been shown to interact with Estrogen receptor alpha, CTNNAL1 and PRKAR2A.-Further reading:...
, CBFA2T3
CBFA2T3
Protein CBFA2T3 is a protein that in humans is encoded by the CBFA2T3 gene.-Interactions:CBFA2T3 has been shown to interact with HDAC1, HDAC3, TCF3, LDB1, TAL1, RUNX1T1 and PRKAR2A.-Further reading:...
and PDE4A
PDE4A
cAMP-specific 3',5'-cyclic phosphodiesterase 4A is an enzyme that in humans is encoded by the PDE4A gene.-Further reading:...
.
See also
- Protein kinaseProtein kinaseA protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them . Phosphorylation usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins...
- AMPKAMP-activated protein kinase5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme that plays a role in cellular energy homeostasis. It consists of three proteins that together make a functional enzyme, conserved from yeast to humans. It is expressed in a number of...
- cAMPCyclic adenosine monophosphateCyclic adenosine monophosphate is a second messenger important in many biological processes...