Pablo Rubinstein
Encyclopedia
Pablo Rubinstein is a pioneer (during the 1980s) in freezing of umbilical cord blood
or placental blood cells for the use for unrelated donors to treat diseases like Leukemia
and genetic diseases such as Taysachs and Sickle Cell Anemia. He pioneered and established an international cord blood banking system and has played a leading role in international cord blood transplantation.
degree from the Universidad de Chile
in 1962, Rubinstein completed a surgical residency at Hospital Clinico Jose Joaquin Aguiree in Chile
and completed a fellowship at M.I. Bassett Hospital at Columbia University
. He also finished an international fellowship at the National Institutes of Health
at Mount Sinai Hospital
in New York
. He also taught as a professor at Universidad de Chile for four years.
, in order to establish the inventory of stem cell units necessary to provide unrelated, matched grafts for patients.
In 1993, Joanne Kurtzberg, Duke University Medical Center, performed the first two successful unrelated donor cord blood transplants; one of which cured acute lymphoblastic leukemia (ALL). As of 2006, more than 7,000 transplants from unrelated donors have been conducted on patients worldwide.
. Along with his co-founder, Cladd Stevens, he and the program have enabled the inventory of umbilical cord blood units from ethnically diverse donors to grow, enabling it to serve the needs of patients across the world.
He began in as an investigator at the Lindsley F. Kimball Research Institute at the NYBC, and serves as director of the Fred H. Allen Jr. Laboratory of Immunogenetics.
Rubinstein is also an adjunct clinical professor at Columbia University and is the author of more than 200 research papers on immunogenetics, cord blood banking and transplantation.
and House of Representatives
on the importance of expanding funding Stem Cell research, and writes articles and papers on similar topics.
Cord blood
Umbilical cord blood is blood that remains in the placenta and in the attached umbilical cord after childbirth. Cord blood is collected because it contains stem cells which can be used to treat hematopoietic and genetic disorders.-Collection:...
or placental blood cells for the use for unrelated donors to treat diseases like Leukemia
Leukemia
Leukemia or leukaemia is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases...
and genetic diseases such as Taysachs and Sickle Cell Anemia. He pioneered and established an international cord blood banking system and has played a leading role in international cord blood transplantation.
Medical Background
Earning his M.D.Doctor of Medicine
Doctor of Medicine is a doctoral degree for physicians. The degree is granted by medical schools...
degree from the Universidad de Chile
Universidad de Chile (university)
The University of Chile is the largest and oldest institution of higher education in Chile and one of the oldest in the Americas. Founded in 1842 as the replacement and continuation of the former colonial Royal University of San Felipe , the university is often called Casa de Bello in honor of...
in 1962, Rubinstein completed a surgical residency at Hospital Clinico Jose Joaquin Aguiree in Chile
Chile
Chile ,officially the Republic of Chile , is a country in South America occupying a long, narrow coastal strip between the Andes mountains to the east and the Pacific Ocean to the west. It borders Peru to the north, Bolivia to the northeast, Argentina to the east, and the Drake Passage in the far...
and completed a fellowship at M.I. Bassett Hospital at Columbia University
Columbia University
Columbia University in the City of New York is a private, Ivy League university in Manhattan, New York City. Columbia is the oldest institution of higher learning in the state of New York, the fifth oldest in the United States, and one of the country's nine Colonial Colleges founded before the...
. He also finished an international fellowship at the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
at Mount Sinai Hospital
Mount Sinai Hospital, New York
Mount Sinai Hospital, founded in 1852, is one of the oldest and largest teaching hospitals in the United States. In 2011-2012, Mount Sinai Hospital was ranked as one of America's best hospitals by U.S...
in New York
New York
New York is a state in the Northeastern region of the United States. It is the nation's third most populous state. New York is bordered by New Jersey and Pennsylvania to the south, and by Connecticut, Massachusetts and Vermont to the east...
. He also taught as a professor at Universidad de Chile for four years.
History of Cord Blood Transplants
Following the first sibling-donor cord blood transplant in 1988, the National Institute of Health (NIH) awarded a grant to Rubinstein to develop the world's first cord blood program at the New York Blood CenterNew York Blood Center
New York Blood Center bills itself as the "nation's largest, community-based, non-profit, independent blood center." Founded in 1964, it relies upon a staff of 2,000 workers and a much smaller permanent staff in order to supply over 200 hospitals in New York and New Jersey with a source of whole...
, in order to establish the inventory of stem cell units necessary to provide unrelated, matched grafts for patients.
In 1993, Joanne Kurtzberg, Duke University Medical Center, performed the first two successful unrelated donor cord blood transplants; one of which cured acute lymphoblastic leukemia (ALL). As of 2006, more than 7,000 transplants from unrelated donors have been conducted on patients worldwide.
National Cord Blood Program
Rubinstein is co-founder and director, of the National Cord Blood Program at the New York Blood CenterNew York Blood Center
New York Blood Center bills itself as the "nation's largest, community-based, non-profit, independent blood center." Founded in 1964, it relies upon a staff of 2,000 workers and a much smaller permanent staff in order to supply over 200 hospitals in New York and New Jersey with a source of whole...
. Along with his co-founder, Cladd Stevens, he and the program have enabled the inventory of umbilical cord blood units from ethnically diverse donors to grow, enabling it to serve the needs of patients across the world.
Medical Focus
Rubinstein specializes in immunogenetics, which encompasses the structure and function of genes that regulate immune responses, control the acceptance or rejection of tissue and organ transplants, and affect susceptibility to certain diseases.He began in as an investigator at the Lindsley F. Kimball Research Institute at the NYBC, and serves as director of the Fred H. Allen Jr. Laboratory of Immunogenetics.
Rubinstein is also an adjunct clinical professor at Columbia University and is the author of more than 200 research papers on immunogenetics, cord blood banking and transplantation.
Stem Cell Advocate
Rubinstein has testified to the United States SenateUnited States Senate
The United States Senate is the upper house of the bicameral legislature of the United States, and together with the United States House of Representatives comprises the United States Congress. The composition and powers of the Senate are established in Article One of the U.S. Constitution. Each...
and House of Representatives
United States House of Representatives
The United States House of Representatives is one of the two Houses of the United States Congress, the bicameral legislature which also includes the Senate.The composition and powers of the House are established in Article One of the Constitution...
on the importance of expanding funding Stem Cell research, and writes articles and papers on similar topics.