Palmatine
Encyclopedia
Palmatine is a protoberberine alkaloid
found in several plants including Phellodendron amurense
, Rhizoma coptidis/Coptis Chinensis
and Corydalis yanhusuo.
It is the major component of the protoberberine extract from Enantia chlorantha.
It has been used in the treatment of jaundice
, dysentery
, hypertension
, inflammation
, and liver-related diseases.
This compound could potentially be developed for the treatment of flavivirus
infections
Alkaloid
Alkaloids are a group of naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids...
found in several plants including Phellodendron amurense
Phellodendron amurense
Phellodendron amurense Rupr. is a species of tree in the family Rutaceae, commonly called the Amur cork tree. It is a major source of huáng bò , one of the 50 fundamental herbs used in traditional Chinese medicine...
, Rhizoma coptidis/Coptis Chinensis
Coptis chinensis
The Chinese goldthread is a species of goldthread native to China.-Etymology:*Coptis chinensis Franch. var. chinensis**The Chinese goldthread (Coptis chinensis) is a species of goldthread native to China.-Etymology:*Coptis chinensis Franch. var. chinensis**The Chinese goldthread (Coptis chinensis)...
and Corydalis yanhusuo.
It is the major component of the protoberberine extract from Enantia chlorantha.
It has been used in the treatment of jaundice
Jaundice
Jaundice is a yellowish pigmentation of the skin, the conjunctival membranes over the sclerae , and other mucous membranes caused by hyperbilirubinemia . This hyperbilirubinemia subsequently causes increased levels of bilirubin in the extracellular fluid...
, dysentery
Dysentery
Dysentery is an inflammatory disorder of the intestine, especially of the colon, that results in severe diarrhea containing mucus and/or blood in the faeces with fever and abdominal pain. If left untreated, dysentery can be fatal.There are differences between dysentery and normal bloody diarrhoea...
, hypertension
Hypertension
Hypertension or high blood pressure is a cardiac chronic medical condition in which the systemic arterial blood pressure is elevated. What that means is that the heart is having to work harder than it should to pump the blood around the body. Blood pressure involves two measurements, systolic and...
, inflammation
Inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...
, and liver-related diseases.
This compound could potentially be developed for the treatment of flavivirus
Flavivirus
Flavivirus is a genus of the family Flaviviridae. This genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, and several other viruses which may cause encephalitis....
infections