Parasite Eve
Encyclopedia
Parasite Eve is a Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

ese science fiction
Science fiction
Science fiction is a genre of fiction dealing with imaginary but more or less plausible content such as future settings, futuristic science and technology, space travel, aliens, and paranormal abilities...

 novel
Novel
A novel is a book of long narrative in literary prose. The genre has historical roots both in the fields of the medieval and early modern romance and in the tradition of the novella. The latter supplied the present generic term in the late 18th century....

 by Hideaki Sena
Hideaki Sena
is a Japanese pharmacologist and novelist. Sena was a graduate student at Tohoku University when he wrote his prizewinning debut novel, Parasite Eve. The novel was adapted into a film and a popular horror role-playing game by Square. He is also the author of Brain Valley, for which he won the Nihon...

, first published in Kadokawa Horror Bunko in 1996. The book was published in North America by Vertical, Inc. in 2005.

Parasite Eve has been adapted into a 1997 film and a 1998 video game
Parasite Eve (video game)
is a horror action role-playing game developed by SquareSoft . The game is a sequel to the novel Parasite Eve, written by Hideaki Sena. It is the first game in the Parasite Eve series.-Gameplay:...

 for the Sony
Sony
, commonly referred to as Sony, is a Japanese multinational conglomerate corporation headquartered in Minato, Tokyo, Japan and the world's fifth largest media conglomerate measured by revenues....

 PlayStation
PlayStation
The is a 32-bit fifth-generation video game console first released by Sony Computer Entertainment in Japan on December 3, .The PlayStation was the first of the PlayStation series of consoles and handheld game devices. The PlayStation 2 was the console's successor in 2000...

 by Square
Square (company)
was a Japanese video game company founded in September 1983 by Masafumi Miyamoto. It merged with Enix in 2003 and became part of Square Enix...

 (now Square Enix
Square Enix
is a Japanese video game and publishing company best known for its console role-playing game franchises, which include the Final Fantasy series, the Dragon Quest series, and the action-RPG Kingdom Hearts series...

). Two sequels to the game were released.

Plot summary

Mitochondria are the "energy factories" of biological cells. It is thought that they were originally separate organisms, and a symbiotic relationship between them and early cellular life has evolved into their present position as cell organelles with no independent existence (see endosymbiotic theory
Endosymbiotic theory
The endosymbiotic theory concerns the mitochondria, plastids , and possibly other organelles of eukaryotic cells. According to this theory, certain organelles originated as free-living bacteria that were taken inside another cell as endosymbionts...

).

The novel's plot supposes that mitochondria, which are inherited through the female line of descent, form the dispersed body of an intelligent conscious life-form, dubbed Eve, which has been waiting throughout history and evolution for the right conditions when mitochondrial life can achieve its true potential and take over from eukaryotic life-forms (i.e. humans and similar life) by causing a child to be born that can control its own genetic code.

Eve is able to control people's minds and bodies by signaling to the mitochondria in their bodies. She can cause certain thoughts to occur to them and also make them undergo spontaneous combustion
Spontaneous human combustion
Spontaneous human combustion describes reported cases of the burning of a living human body without an apparent external source of ignition...

.

The conditions Eve has waited for have arrived; she has found the perfect host in the body of Kiyomi Nagishima. At the start of the book, Eve is the mitochondria in Kiyomi's body. She causes Kiyomi to crash her car; Kiyomi survives but is brain dead. Kiyomi's husband is Toshiaki, a research assistant teaching and researching biological science. Eve influences Toshiaki and a doctor to ensure that one of Kiyomi's kidneys is transplanted into the teenage girl Mariko Anzai as an organ donation. As part of Kiyomi's body, the kidney is also a part of Eve; this prepares Mariko to be a suitable host for giving birth to mitochondrial life, as her immune system would otherwise rebel.

Eve influences Toshiaki to grow some of Kiyomi's liver cells in his lab in sufficient quantities to provide Eve with an independent body, he thinks that he is doing this as an experiment using different cultures of the liver cells. Forming some of the cells into a body, Eve possesses Toshiaki's assistant Sachiko Asakura and intermittently takes control of Asakura to work upon the cultures. Eventually, she takes control of Asakura during a conference presentation speech and announces her presence. Leaving Asakura's body, she returns to the lab. Toshiaki pursues her, and she rapes him in the form of Kiyomi to capture some of his sperm, which she uses to fertilize an egg of her own production. Moving to the hospital, she implants this egg in Mariko's womb. The egg develops into a child that is born almost immediately.

Eve anticipates that her child will be able to consciously change its genetic code, thus being an infinitely adaptable "perfect life form" capable of replacing humanity and similar life-forms. Mariko's body will be host to a new race of these life-forms.

The experiment fails, since Toshiaki's sperm carry a separate line of "male" mitochondria (inherited through sperm) that will be wiped out in the new order; these resist the change by fighting for control of the child's body, causing it to switch between male and female forms. The child dies; Toshiaki also dies, merging his body with the child's to control the bursts of psychokinetic-like power it gives out in its death throes that threaten to kill many people.

In the novel's epilogue, it is revealed that some samples of the Eve cells in Toshiaki's lab survived. Fortunately, they are destroyed shortly after being found.

Film, TV or theatrical adaptations

The novel was adapted into a film, which was released in 1997 in Japan, and on Region 1 DVD in 2001.

Video game

A sequel to the novel appeared in the form of the Square
Square Enix
is a Japanese video game and publishing company best known for its console role-playing game franchises, which include the Final Fantasy series, the Dragon Quest series, and the action-RPG Kingdom Hearts series...

 Survivor RPG Parasite Eve, along with one sequel and a spin-off game.
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