Paul Bach-y-Rita
Encyclopedia
Paul Bach-y-Rita was an American neuroscientist whose most notable work was in the field of neuroplasticity
Neuroplasticity
Neuroplasticity is a non-specific neuroscience term referring to the ability of the brain and nervous system in all species to change structurally and functionally as a result of input from the environment. Plasticity occurs on a variety of levels, ranging from cellular changes involved in...

. Bach-y-Rita was one of the first to seriously study the idea of neuroplasticity (although it was first proposed in the late 19th century), and to introduce sensory substitution as a tool to treat patients suffering from neurological disorders.

Biography

Bach-y-Rita was born on April 4, 1934, in New York City
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...

 to Anne Hyman and Pedro Bach-y-Rita , and studied at the Bronx High School of Science
Bronx High School of Science
The Bronx High School of Science is a specialized New York City public high school often considered the premier science magnet school in the United States. Founded in 1938, it is now located in the Bedford Park section of the Bronx...

, from which he graduated at the age of fifteen before studying at Mexico City College
Mexico City College
Mexico City College was founded in 1940, as an English speaking junior college in Mexico City, Mexico.In 1946 the college switched to a 4 year Bachelor of Arts degree-awarding institution, then changed its name to University of the Americas in 1963 and in 1968 to Universidad de las Americas,...

 (now the University of the Americas in Puebla). After his early education, he studied medicine at Universidad Nacional Autónoma de México (UNAM). He initially dropped out, going through several varied jobs, but later returned to finish his degree.

After completing his degree, Bach-y-Rita worked for a short time as a physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

 in the village of Tilzaptla in Morelos, Mexico, before working for ten years at the Smith-Kettlewell Institute
Smith-Kettlewell Institute
The Smith-Kettlewell Eye Research Institute in San Francisco was formed in 1959 by Arthur Jampolsky on the former campus of the Stanford Medical School.The current interim director of Smith-Kettlewell is Arthur Jampolsky.Major Work:...

 of Visual Sciences in San Francisco, becoming a professor at the age of 37. He joined the University of Wisconsin–Madison
University of Wisconsin–Madison
The University of Wisconsin–Madison is a public research university located in Madison, Wisconsin, United States. Founded in 1848, UW–Madison is the flagship campus of the University of Wisconsin System. It became a land-grant institution in 1866...

 in 1983 and became a professor at UW Medical school, Department of Orthopedics and Rehabilitation Medicine and the UW–Madison Engineering School, Department of Biomedical Engineering, while working at other organisations around the world. Bach-y-Rita died at his home on November 20, 2006.

Work in Sensory Substitution and Neuroplasticity

Bach-y-Rita's most notable work was in the field of neuroplasticity
Neuroplasticity
Neuroplasticity is a non-specific neuroscience term referring to the ability of the brain and nervous system in all species to change structurally and functionally as a result of input from the environment. Plasticity occurs on a variety of levels, ranging from cellular changes involved in...

. He is seen as the first to propose the concept of sensory substitution
Sensory substitution
Sensory substitution means to transform the characteristics of one sensory modality into stimuli of another sensory modality. It is hoped that sensory substitution systems can help handicapped people by restoring their ability to perceive a certain defective sensory modality by using sensory...

 to treat patients with disabilities, often those caused by neurological problems. One of the first applications of sensory substitution he created was a chair which allowed blind people to 'see'. The trials he conducted in 1969 are now regarded to be the first form of experimental evidence for neuroplasticity and the feasibility of sensory substitution. Later in his career, Bach-y-Rita created a device which enabled patients with damaged vestibular nuclei to regain their ability to remain balanced, by using an electrical stimulator placed on the tongue which reacted to a motion sensor affixed to the patient. This application enabled patients to remain balanced without the equipment after several weeks use.

Early research in Neuroscience

The chair he used had a bank of four hundred vibrating plates resting against the blind user's back, and vibrating in connection with a camera placed above the chair, looking forwards. The pattern in which the stimulation occurred enabled the user to "see", often being able to recognise an object coming towards the camera. Bach-y-Rita suggested this was an example of neuroplasticity, as he believed the signals sent to the brain from the skin via touch were being processed in the visual cortex
Visual cortex
The visual cortex of the brain is the part of the cerebral cortex responsible for processing visual information. It is located in the occipital lobe, in the back of the brain....

, because of the way the patients interpreted the information.

Using Neuroplasticity to treat balance disorders

One of his last applications of neuroplasticity was to treat patients with damaged vestibular system
Vestibular system
The vestibular system, which contributes to balance in most mammals and to the sense of spatial orientation, is the sensory system that provides the leading contribution about movement and sense of balance. Together with the cochlea, a part of the auditory system, it constitutes the labyrinth of...

s, meaning they were unable to remain balanced. The device he created (now sold as Brainport
Brainport
BrainPort is a technology sold by Wicab Inc. whereby sensory information can be sent to one's brain via a signal from the BrainPort that terminates in an electrode array which sits atop the tongue. It was initially developed by Paul Bach-y-Rita as an aid to people's sense of balance, particularly...

) consists of a group of accelerometers positioned on the patient and linked to a computer. The information is processed and fed to a small plate which is positioned on the patient's tongue (used because of the high density of sensory receptor
Sensory receptor
In a sensory system, a sensory receptor is a sensory nerve ending that responds to a stimulus in the internal or external environment of an organism...

s). The device stimulates different areas of the tongue, depending on the orientation of the accelerometers. This stimulation enables the patient to stay balanced. However, after repeated use , Bach-y-Rita discovered that the patient remained balanced for a short time after using the device. After using the device for several weeks, the patient was completely cured, demonstrating another application of neuroplasticity in treating neurological disorders, and also the ability of the brain to adapt to repeated stimuli. Also created was a similar device that enables a patient to see by way of a camera attaching to his or her head and feeding information to the tongue.

Research into neuroplasticity to treat stroke victims

In 1958, Bach-y-Rita's father, Pedro, suffered a cerebral infarction
Cerebral infarction
A cerebral infarction is the ischemic kind of stroke due to a disturbance in the blood vessels supplying blood to the brain. It can be atherothrombotic or embolic. Stroke caused by cerebral infarction should be distinguished from two other kinds of stroke: cerebral hemorrhage and subarachnoid...

 (stroke) which caused paralysis
Paralysis
Paralysis is loss of muscle function for one or more muscles. Paralysis can be accompanied by a loss of feeling in the affected area if there is sensory damage as well as motor. A study conducted by the Christopher & Dana Reeve Foundation, suggests that about 1 in 50 people have been diagnosed...

 to one side of his body and damaged his ability to speak. George Bach-y-Rita -- a psychiatrist and Paul's brother -- succeeded in treating Pedro so that he was able to lead a normal life, despite the opinion of several doctors that this was impossible. When Pedro died, an autopsy, performed by Dr. Mary Jane Aguilar revealed that Paul's father Pedro had suffered a major stroke and suffered severe damage to a large portion of his brain stem
Brain stem
In vertebrate anatomy the brainstem is the posterior part of the brain, adjoining and structurally continuous with the spinal cord. The brain stem provides the main motor and sensory innervation to the face and neck via the cranial nerves...

, which had not repaired itself after the stroke. The fact that he had made such a significant recovery suggested that his brain had reorganized itself, providing evidence for neuroplasticity.

External links

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