Pennsylvania Route 645 is a state highway in the Commonwealth

Commonwealth

Commonwealth is a traditional English term for a political community founded for the common good. Historically, it has sometimes been synonymous with "republic."More recently it has been used for fraternal associations of some sovereign nations...

 of Pennsylvania

Pennsylvania

The Commonwealth of Pennsylvania is a U.S. state that is located in the Northeastern and Mid-Atlantic regions of the United States. The state borders Delaware and Maryland to the south, West Virginia to the southwest, Ohio to the west, New York and Ontario, Canada, to the north, and New Jersey to...

. The route runs from U.S. Route 422

U.S. Route 422

U.S. Route 422 is a long spur route of US 22 split into two segments in the U.S. states of Ohio and Pennsylvania. The western spur begins in downtown Cleveland, Ohio, and ends at Ebensburg, Pennsylvania...

 in Myerstown

Myerstown, Pennsylvania

Myerstown is a borough located in Lebanon County, Pennsylvania. It is part of the Lebanon, PA Metropolitan Statistical Area. As of the 2000 census, the borough had a total population of 3,171...

, Lebanon County

Lebanon County, Pennsylvania

As of the census of 2000, there were 120,327 people and 32,771 families residing in the county. The population density was 332 people per square mile . There were 49,320 housing units at an average density of 136 per square mile...

 north to Pennsylvania Route 443

Pennsylvania Route 443

Pennsylvania Route 443 is a long east–west state highway in the US state of Pennsylvania. Unlike other state highways, PA 443 terminates at not a traffic route at its west end, but at Front Street, formerly U.S. Route 22 and U.S. Route 322 and presently Quadrant Route 3009, in the...

 in Pine Grove Township

Pine Grove Township, Schuylkill County, Pennsylvania

Pine Grove Township is a township in Schuylkill County, Pennsylvania, United States. The population was 3,930 at the 2000 census.-Geography:...

, Schuylkill County

Schuylkill County, Pennsylvania

-Notable people:*Boxing heavyweight great Muhammad Ali had his training camp in Deer Lake.*Charles Justin Bailey, commanding general of the 81st Division in World War I, was born in Tamaqua on June 21, 1859....

.

Route description

Pennsylvania Route 645 heads north from US 422 on North Locust Street into Jackson Township

Jackson Township, Lebanon County, Pennsylvania

Jackson Township is a township in Lebanon County, Pennsylvania, United States. The population was 6,338 at the 2000 census.-Geography:According to the United States Census Bureau, the township has a total area of , of which, of it is land and of it is water.-Demographics:As of the census of...

. The name changes to Kutztown Road a short distance north of US 422. Pennsylvania Route 645 then heads east for a short distance on East Rosebud Road before turning north on Hilltop Road. It crosses into Bethel Township

Bethel Township, Berks County, Pennsylvania

Bethel Township is a township in Berks County, Pennsylvania, United States. The population was 4,166 at the 2000 census.-Geography:According to the United States Census Bureau, the township has a total area of , of which, of it is land and of it is water. It is drained by the Little Swatara...

 in Berks County

Berks County, Pennsylvania

-Demographics:As of the census of 2000, there were 373,638 people, 141,570 households, and 98,532 families residing in the county. The population density was 435 people per square mile . There were 150,222 housing units at an average density of 175 per square mile...

 where the name changes to Camp Swatara Road. It features an interchange with Interstate 78

Interstate 78

Interstate 78 is an Interstate Highway in the Northeast United States, running 144 miles from Interstate 81 northeast of Harrisburg, Pennsylvania, through Allentown, Pennsylvania, and western and northern New Jersey to the Holland Tunnel and Lower Manhattan in New York City.I-78 is a major road...

/U.S. Route 22

U.S. Route 22

U.S. Route 22 is a west–east route and is one of the original United States highways of 1926, running from Cincinnati, Ohio, at US 27, US 42, US 127, and US 52 to Newark, New Jersey, at U.S. Route 1/9 near the Newark Liberty International Airport.US 22 also carries the names of the William...

 near Frystown

Frystown, Pennsylvania

Frystown is a small, unincorporated community in southwestern Bethel Township, in far western Berks County, Pennsylvania. It is located near the township line with Tulpehocken Township, and the community is served by the Tulpehocken Area School District....

 and then crosses the Blue Mountain

Blue Mountain (Pennsylvania)

Blue Mountain is a ridge that forms the eastern edge of the Appalachian mountain range in the U.S. state of Pennsylvania. It cuts across the eastern half of the state from New Jersey to Maryland, providing a distinct boundary between a number of Pennsylvania's geographical and cultural regions...

 range into Pine Grove Township

Pine Grove Township, Schuylkill County, Pennsylvania

Pine Grove Township is a township in Schuylkill County, Pennsylvania, United States. The population was 3,930 at the 2000 census.-Geography:...

, Schuylkill County and the road name becomes Geary Wolf Road. Pennsylvania Route 645 then continues north to Pennsylvania Route 443 just south of the borough of Pine Grove

Pine Grove, Schuylkill County, Pennsylvania

Pine Grove is a borough in Schuylkill County, Pennsylvania, in the United States. As of the 2000 census, the borough population was 2,154.-Geography:Pine Grove is located at ....

.

Major intersections