Piperlongumine
Encyclopedia
Piperlongumine is a natural product
constituent of the fruit of the Long pepper
(Piper longum), a pepper plant found in southern India and southeast Asia.
Piperlongumine may have anti-cancer properties. It selectively targets and kills cancer cells but leaving normal cells unharmed. "In mice injected with human bladder, breast, lung, or melanoma cancer cells, PL inhibited tumor growth but showed no toxicity in normal mice. In a tougher test of mice that developed breast cancer spontaneously, PL blocked both tumor growth and metastasis."
Natural product
A natural product is a chemical compound or substance produced by a living organism - found in nature that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery and drug design...
constituent of the fruit of the Long pepper
Long pepper
Long pepper , , sometimes called Indian long pepper, is a flowering vine in the family Piperaceae, cultivated for its fruit, which is usually dried and used as a spice and seasoning. Long pepper has a similar, but hotter, taste to its close relative Piper nigrum - from which black, green and white...
(Piper longum), a pepper plant found in southern India and southeast Asia.
Piperlongumine may have anti-cancer properties. It selectively targets and kills cancer cells but leaving normal cells unharmed. "In mice injected with human bladder, breast, lung, or melanoma cancer cells, PL inhibited tumor growth but showed no toxicity in normal mice. In a tougher test of mice that developed breast cancer spontaneously, PL blocked both tumor growth and metastasis."