Pope Pius III born Francesco Todeschini Piccolomini, was Pope

Pope

The Pope is the Bishop of Rome, a position that makes him the leader of the worldwide Catholic Church . In the Catholic Church, the Pope is regarded as the successor of Saint Peter, the Apostle...

 from September 22 to October 18, 1503.
He was born in Siena

Siena

Siena is a city in Tuscany, Italy. It is the capital of the province of Siena.The historic centre of Siena has been declared by UNESCO a World Heritage Site. It is one of the nation's most visited tourist attractions, with over 163,000 international arrivals in 2008...

, the nephew of Aeneas Silvius Piccolomini, the future Pope Pius II

Pope Pius II

Pope Pius II, born Enea Silvio Piccolomini was Pope from August 19, 1458 until his death in 1464. Pius II was born at Corsignano in the Sienese territory of a noble but decayed family...

, by his sister Laodamia. He was received as a boy into the household of Aeneas Silvius, who permitted him to assume the name and arms of the Piccolomini family (his brother Antonio being made Duke of Amalfi

Amalfi

Amalfi is a town and comune in the province of Salerno, in the region of Campania, Italy, on the Gulf of Salerno, c. 35 km southeast of Naples. It lies at the mouth of a deep ravine, at the foot of Monte Cerreto , surrounded by dramatic cliffs and coastal scenery...

 during the pontificate of Pius II).