ProbCons
Encyclopedia
ProbCons is an open source probabilistic consistency-based multiple alignment of amino acid
sequences. It is an efficient protein multiple sequence alignment
program, which has demonstrated a statistically significant improvement in accuracy compared to several leading alignment tools.
Amino acid
Amino acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen...
sequences. It is an efficient protein multiple sequence alignment
Multiple sequence alignment
A multiple sequence alignment is a sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. In many cases, the input set of query sequences are assumed to have an evolutionary relationship by which they share a lineage and are descended from a common ancestor...
program, which has demonstrated a statistically significant improvement in accuracy compared to several leading alignment tools.
See also
- Sequence alignment softwareSequence alignment softwareThis list of sequence alignment software is a compilation of software tools and web portals used in pairwise sequence alignment and multiple sequence alignment...
- ClustalClustalClustal is a widely used multiple sequence alignment computer program. The latest version is 2.1. There are two main variations:*ClustalW: command line interface*ClustalX: This version has a graphical user interface...
- MUSCLE
- AMAPAMAPAMAP is a multiple sequence alignment program based on a new approach to multiple alignment called sequence annealing. This approach consists of building up the multiple alignment one match at a time, thereby circumventing many of the problems of progressive alignment...
- T-CoffeeT-CoffeeT-Coffee is a multiple sequence alignment software using a progressive approach. It generates a library of pairwise alignments to guide the multiple sequence alignment...
- ProbConsRNA — for nucleotideNucleotideNucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. In addition, nucleotides participate in cellular signaling , and are incorporated into important cofactors of enzymatic reactions...
sequences