Procollagen peptidase
Encyclopedia
Procollagen peptidase is an endopeptidase
involved in the processing of collagen
. The proteases removes the terminal peptides of the procollagen. Deficiency of these enzymes leads to dermatosparaxis or ehlers Danlos syndrome.
The enzyme is present in the skin of rats and humans.
Endopeptidase
Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids , in contrast to exopeptidases, which break peptide bonds from their end-pieces. For this reason, endopeptidases cannot break down peptides into monomers, while exopeptidases can break...
involved in the processing of collagen
Collagen
Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content...
. The proteases removes the terminal peptides of the procollagen. Deficiency of these enzymes leads to dermatosparaxis or ehlers Danlos syndrome.
The enzyme is present in the skin of rats and humans.
External links
- The MEROPSMeropsMerops may refer to:* Merops , a genus of bee-eaters.* MEROPS, an on-line database for peptidases.It may also refer to several figures from Greek mythology:* King of Ethiopia, husband of Clymene, who lay with Helios and bore Phaethon...
online database for peptidases and their inhibitors: Procollagen C-Peptidase:M12.005, Procollagen N-Peptidase:M12.301