Protein inhibitor of activated STAT2
Encyclopedia
E3 SUMO-protein ligase PIAS2 is an enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that in humans is encoded by the PIAS2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Interactions

Protein inhibitor of activated STAT2 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with Androgen receptor
Androgen receptor
The androgen receptor , also known as NR3C4 , is a type of nuclear receptor that is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus...

, DNMT3A
DNMT3A
DNA -methyltransferase 3A is an enzyme that in humans is encoded by the DNMT3A gene.-Interactions:DNMT3A has been shown to interact with ZNF238, HDAC1, Myc, Protein inhibitor of activated STAT2, DNMT1, DNMT3B, PIAS1, UBE2I and SUV39H1....

, PARK7
PARK7
Parkinson disease 7, also known as PARK7, is a protein which in humans is encoded by the PARK7 gene. It is also known as DJ-1.- Function :...

 and UBE2I
UBE2I
SUMO-conjugating enzyme UBC9 is a protein that in humans is encoded by the UBE2I gene.-Interactions:UBE2I has been shown to interact with WT1, TOP1, RAD51, Activating transcription factor 2, PIAS1, SALL1, FHIT, RANBP2, Protein inhibitor of activated STAT2, DNMT3A, DNMT3B, Small ubiquitin-related...

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Further reading

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