Pumiliotoxins are one of several toxins found in the skin of poison dart frog

Poison dart frog

Poison dart frog is the common name of a group of frogs in the family Dendrobatidae which are native to Central and South America. These species are diurnal and often have brightly-colored bodies...

s. Closely related, though more toxic, are allopumiliotoxin

Allopumiliotoxin

Allopumiliotoxins are a structural division in the pumiliotoxin-A class of alkaloids. The compounds of the pumiliotoxin-A class are primarily found in the skins of frogs, toads, and other amphibians and are used as a chemical defense mechanism to ward off predators, microorganisms, and ectoparasites...

s, (aPTXs). Other toxins found in the skin of poison frogs include decahydroquinolines (DHQs), izidines, coccinellines, and spiropyrrolizidines. Pumiliotoxins are very poisonous in high concentration. Pumiliotoxins are much weaker than that of the batrachotoxin

Batrachotoxin

Batrachotoxins are extremely potent cardiotoxic and neurotoxic steroidal alkaloids found in certain species of frogs , melyrid beetles, and birds...

s, they can be between 100-1000 times weaker.