RHCG
Encyclopedia
Rh family, C glycoprotein, also known as RHCG, is a protein
which in humans is encoded by the RHCG gene
.
handling and pH homeostasis
in the kidney. The structure of the RHCG protein indicates that it has a hydrophobic ammonia
-conducting channel thus making it an ammonia transporter
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
which in humans is encoded by the RHCG gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
RHCG plays a critical role in ammoniumAmmonium
The ammonium cation is a positively charged polyatomic cation with the chemical formula NH. It is formed by the protonation of ammonia...
handling and pH homeostasis
Homeostasis
Homeostasis is the property of a system that regulates its internal environment and tends to maintain a stable, constant condition of properties like temperature or pH...
in the kidney. The structure of the RHCG protein indicates that it has a hydrophobic ammonia
Ammonia
Ammonia is a compound of nitrogen and hydrogen with the formula . It is a colourless gas with a characteristic pungent odour. Ammonia contributes significantly to the nutritional needs of terrestrial organisms by serving as a precursor to food and fertilizers. Ammonia, either directly or...
-conducting channel thus making it an ammonia transporter
Ammonia transporter
Ammonia transporters are structurally related membrane transport proteins called Amt proteins , methylammonium/ammonium permeases or RhAG, RhBG, and RhCG Rh family members in mammals. The RhAG, RhBG and RhCG proteins constitute solute carrier family 42...
.