RHOB
Encyclopedia
Ras homolog gene family, member B, also known as RHOB, is a protein
which in humans is encoded by the RHOB gene
.
RHOB is a member of the Rho GTP-binding protein
family.
with CIT
, ARHGEF3
, ARHGDIG
and RHPN2
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
which in humans is encoded by the RHOB gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
RHOB is a member of the Rho GTP-binding protein
Rho family of GTPases
The Rho family of GTPases is a family of small signaling G protein , and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have been shown to regulate many aspects of intracellular actin dynamics, and are found in all eukaryotic organisms including yeasts and some plants...
family.
Interactions
RHOB has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with CIT
CIT (gene)
Citron Rho-interacting kinase is an enzyme that in humans is encoded by the CIT gene.-Interactions:CIT has been shown to interact with RHOB and RHOA.-Further reading:...
, ARHGEF3
ARHGEF3
Rho guanine nucleotide exchange factor 3, also known as ARHGEF3, is a human gene.-Interactions:ARHGEF3 has been shown to interact with RHOB and RHOA.-Further reading:...
, ARHGDIG
ARHGDIG
Rho GDP-dissociation inhibitor 3 is a protein that in humans is encoded by the ARHGDIG gene.-Further reading:...
and RHPN2
RHPN2
Rhophilin-2 is a protein that in humans is encoded by the RHPN2 gene.-Further reading:...
.
Further reading
See also
- neural crestNeural crestNeural crest cells are a transient, multipotent, migratory cell population unique to vertebrates that gives rise to a diverse cell lineage including melanocytes, craniofacial cartilage and bone, smooth muscle, peripheral and enteric neurons and glia....