RNA of unknown function
Encyclopedia
RNA of unknown function (RUF) is a generic name, often appended with a numeric identifier, for a non-coding RNA
molecule which has been partially-characterised or predicted but the biological function has yet to be determined. The same convention is used for protein
s, they can be named domains of unknown function
(DUFs).
Examples of RUFs include:
RNA of unknown function (RUF) is a generic name, often appended with a numeric identifier, for a non-coding RNA
molecule which has been partially-characterised or predicted but the biological function has yet to be determined. The same convention is used for protein
s, they can be named domains of unknown function
(DUFs).
Examples of RUFs include:
RNA of unknown function (RUF) is a generic name, often appended with a numeric identifier, for a non-coding RNA
molecule which has been partially-characterised or predicted but the biological function has yet to be determined. The same convention is used for protein
s, they can be named domains of unknown function
(DUFs).
Examples of RUFs include:
Non-coding RNA
A non-coding RNA is a functional RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA , non-messenger RNA and functional RNA . The term small RNA is often used for short bacterial ncRNAs...
molecule which has been partially-characterised or predicted but the biological function has yet to be determined. The same convention is used for protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
s, they can be named domains of unknown function
Domain of unknown function
A Domain of unknown function is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220...
(DUFs).
Examples of RUFs include:
- RUF1-8 found in Saccharomyces cerevisiaeSaccharomyces cerevisiaeSaccharomyces cerevisiae is a species of yeast. It is perhaps the most useful yeast, having been instrumental to baking and brewing since ancient times. It is believed that it was originally isolated from the skin of grapes...
, though three of these were later reclassified due to experimental errors
RNA of unknown function (RUF) is a generic name, often appended with a numeric identifier, for a non-coding RNA
Non-coding RNA
A non-coding RNA is a functional RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA , non-messenger RNA and functional RNA . The term small RNA is often used for short bacterial ncRNAs...
molecule which has been partially-characterised or predicted but the biological function has yet to be determined. The same convention is used for protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
s, they can be named domains of unknown function
Domain of unknown function
A Domain of unknown function is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220...
(DUFs).
Examples of RUFs include:
- RUF1-8 found in Saccharomyces cerevisiaeSaccharomyces cerevisiaeSaccharomyces cerevisiae is a species of yeast. It is perhaps the most useful yeast, having been instrumental to baking and brewing since ancient times. It is believed that it was originally isolated from the skin of grapes...
, though three of these were later reclassified due to experimental errors
RNA of unknown function (RUF) is a generic name, often appended with a numeric identifier, for a non-coding RNA
Non-coding RNA
A non-coding RNA is a functional RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA , non-messenger RNA and functional RNA . The term small RNA is often used for short bacterial ncRNAs...
molecule which has been partially-characterised or predicted but the biological function has yet to be determined. The same convention is used for protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
s, they can be named domains of unknown function
Domain of unknown function
A Domain of unknown function is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220...
(DUFs).
Examples of RUFs include:
- RUF1-8 found in Saccharomyces cerevisiaeSaccharomyces cerevisiaeSaccharomyces cerevisiae is a species of yeast. It is perhaps the most useful yeast, having been instrumental to baking and brewing since ancient times. It is believed that it was originally isolated from the skin of grapes...
, though three of these were later reclassified due to experimental errors - RUF20-23 also from S. cerevisiae
- RUF1-6 found in Plasmodium falciparumPlasmodium falciparumPlasmodium falciparum is a protozoan parasite, one of the species of Plasmodium that cause malaria in humans. It is transmitted by the female Anopheles mosquito. Malaria caused by this species is the most dangerous form of malaria, with the highest rates of complications and mortality...
in 2007