Random match possibility
Encyclopedia
Random Match Possibility (RMP) is a kind of measure in population genetics
to measure the possibility of a person randomly picked out of the general population and matching the genotype measured exactly.
A genotype
has a number of allele
s, and each allele has a frequency
in a certain race. This frequency is the RMP of that allele. To calculate the RMP of a certain genotype, multiply the frequencies of the alleles in the genotype together. This will give the RMP of the genotype. In forensic science, the evidence from the crime scene is gathered and the genotype of DNA evidence is collected. This is then matched with the suspect. The RMP of the evidence is useful in convincing the jury, because the chances of the genotype of the evidence and that of the suspect matching is very low, and therefore it can hardly be claimed that the suspect is innocent, as the chances of it being so is very low.
Population genetics
Population genetics is the study of allele frequency distribution and change under the influence of the four main evolutionary processes: natural selection, genetic drift, mutation and gene flow. It also takes into account the factors of recombination, population subdivision and population...
to measure the possibility of a person randomly picked out of the general population and matching the genotype measured exactly.
A genotype
Genotype
The genotype is the genetic makeup of a cell, an organism, or an individual usually with reference to a specific character under consideration...
has a number of allele
Allele
An allele is one of two or more forms of a gene or a genetic locus . "Allel" is an abbreviation of allelomorph. Sometimes, different alleles can result in different observable phenotypic traits, such as different pigmentation...
s, and each allele has a frequency
Allele frequency
Allele frequency or Gene frequency is the proportion of all copies of a gene that is made up of a particular gene variant . In other words, it is the number of copies of a particular allele divided by the number of copies of all alleles at the genetic place in a population. It can be expressed for...
in a certain race. This frequency is the RMP of that allele. To calculate the RMP of a certain genotype, multiply the frequencies of the alleles in the genotype together. This will give the RMP of the genotype. In forensic science, the evidence from the crime scene is gathered and the genotype of DNA evidence is collected. This is then matched with the suspect. The RMP of the evidence is useful in convincing the jury, because the chances of the genotype of the evidence and that of the suspect matching is very low, and therefore it can hardly be claimed that the suspect is innocent, as the chances of it being so is very low.