Replichore
Encyclopedia
The Escherichia coli
chromosome shows two main levels of global organization, macrodomain
s and replichores. In E. coli chromosomes, the origin and terminus of replication divide the genome into oppositely replicated halves called replichores. Replichore 1, which is replicated clockwise, has the presented strand of E. coli as its leading strand; in replichore 2 the complementary strand is the leading one. Many features of E. coli are oriented with respect to replication.
Escherichia coli
Escherichia coli is a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms . Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in humans, and are occasionally responsible for product recalls...
chromosome shows two main levels of global organization, macrodomain
Macrodomain
The Escherichia coli chromosome shows two main levels of global organization, macrodomains and replichores. Macrodomains were discovered by cytological studies. They contain loci showing the same intracellular positioning and choreography during the cell cycle....
s and replichores. In E. coli chromosomes, the origin and terminus of replication divide the genome into oppositely replicated halves called replichores. Replichore 1, which is replicated clockwise, has the presented strand of E. coli as its leading strand; in replichore 2 the complementary strand is the leading one. Many features of E. coli are oriented with respect to replication.