Ribosomal S15 leader
Encyclopedia
The E. coli ribosomal S15 leader is an RNA element
that can form two alternative structures found in the ribosomal S15 protein. One of the two alternate structures is a series of three hairpins
, the other includes a pseudoknot
. This structure causes translational regulation of the S15 protein
. Only the final two hairpins are conserved in other species.
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
that can form two alternative structures found in the ribosomal S15 protein. One of the two alternate structures is a series of three hairpins
Stem-loop
Stem-loop intramolecular base pairing is a pattern that can occur in single-stranded DNA or, more commonly, in RNA. The structure is also known as a hairpin or hairpin loop. It occurs when two regions of the same strand, usually complementary in nucleotide sequence when read in opposite directions,...
, the other includes a pseudoknot
Pseudoknot
A pseudoknot is a nucleic acid secondary structure containing at least two stem-loop structures in which half of one stem is intercalated between the two halves of another stem. The pseudoknot was first recognized in the turnip yellow mosaic virus in 1982...
. This structure causes translational regulation of the S15 protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
. Only the final two hairpins are conserved in other species.