Rnd (GTPase)
Encyclopedia
Rnd is a subclass of the Rho family of GTPase
GTPase
GTPases are a large family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate . The GTP binding and hydrolysis takes place in the highly conserved G domain common to all GTPases.-Functions:...

s, and includes:
  • Rnd1
    Rnd1
    Rnd1 is a small signaling G protein , and is a member of the Rnd subgroup of the Rho family of GTPases.. It is encoded by the gene RND1....

  • Rnd2
    Rnd2
    Rnd2 is a small signaling G protein , and is a member of the Rnd subgroup of the Rho family of GTPases.. It is encoded by the gene RND2....

  • Rnd3
    Rnd3
    Rnd3 is a small signaling G protein , and is a member of the Rnd subgroup of the Rho family of GTPases. It is encoded by the gene RND3....

     (also called RhoE)


Functions include downregulation of stress fibres and focal adhesion
Focal adhesion
In cell biology, focal adhesions are specific types of large macromolecular assemblies through which both mechanical force and regulatory signals are transmitted. More precisely, they can be considered as sub-cellular macromolecules that mediate the regulatory effects In cell biology, focal...

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