SMG6
Encyclopedia
Telomerase-binding protein EST1A is an enzyme
that in humans is encoded by the SMG6 gene
. The C-terminus of the EST1A protein contains a PIN domain
. This structure for this domain has been determined by X-ray crystallography
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the SMG6 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. The C-terminus of the EST1A protein contains a PIN domain
PIN domain
In molecular biology the PIN domain is a protein domain that is about 130 amino acids in length. The PIN domain was named after its identification in the N-terminus of the PilT protein . PIN domains function as nuclease enzymes that cleave single stranded RNA in a sequence dependent manner.PIN...
. This structure for this domain has been determined by X-ray crystallography
X-ray crystallography
X-ray crystallography is a method of determining the arrangement of atoms within a crystal, in which a beam of X-rays strikes a crystal and causes the beam of light to spread into many specific directions. From the angles and intensities of these diffracted beams, a crystallographer can produce a...
.