SPhos
Encyclopedia
SPhos is an organophosphorus compound derived from biphenyl
. Its palladium complexes exhibit high activity for Suzuki coupling
reactions involving aryl chlorides, which are unreactive with palladium complexes of most other phosphine ligand
s. The ligand has convenient handling characteristics since it is air-stable.
Biphenyl
Biphenyl is an organic compound that forms colorless crystals. It has a distinctively pleasant smell. Biphenyl is an aromatic hydrocarbon with a molecular formula 2...
. Its palladium complexes exhibit high activity for Suzuki coupling
Suzuki reaction
The Suzuki reaction is the organic reaction of an aryl- or vinyl-boronic acid with an aryl- or vinyl-halide catalyzed by a palladium complex. It is widely used to synthesize poly-olefins, styrenes, and substituted biphenyls, and has been extended to incorporate alkyl bromides...
reactions involving aryl chlorides, which are unreactive with palladium complexes of most other phosphine ligand
Ligand
In coordination chemistry, a ligand is an ion or molecule that binds to a central metal atom to form a coordination complex. The bonding between metal and ligand generally involves formal donation of one or more of the ligand's electron pairs. The nature of metal-ligand bonding can range from...
s. The ligand has convenient handling characteristics since it is air-stable.