STAT2
Encyclopedia
Signal transducer and activator of transcription 2 is a protein
that in humans is encoded by the STAT2 gene
.
with MED14
, CREB-binding protein, SMARCA4
, STAT1
, IFNAR2
, IFNAR1
and ISGF3G
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the STAT2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
STAT2 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with MED14
MED14
Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene.-Interactions:MED14 has been shown to interact with PPARGC1A, Estrogen receptor alpha, STAT2, Cyclin-dependent kinase 8, Glucocorticoid receptor and Hepatocyte nuclear factor 4...
, CREB-binding protein, SMARCA4
SMARCA4
Transcription activator BRG1 also known as ATP-dependent helicase SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene.- Function :...
, STAT1
STAT1
STAT1 is a member of the Signal Transducers and Activators of Transcription family of transcription factors. STAT1 is involved in upregulating genes due to a signal by either type I, type II or type III interferons...
, IFNAR2
IFNAR2
Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene.-Interactions:IFNAR2 has been shown to interact with STAT2, STAT1, GNB2L1 and IFNA2.-Further reading:...
, IFNAR1
IFNAR1
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.-Interactions:IFNAR1 has been shown to interact with STAT2, Tyrosine kinase 2 and PRMT1.-Further reading:...
and ISGF3G
ISGF3G
Interferon regulatory factor 9 is a protein that in humans is encoded by the IRF9 gene.-Interactions:ISGF3G has been shown to interact with STAT2 and STAT1....
.