Salvia dominica
Encyclopedia
Salvia dominica is a kingdom on the East Bank of the River Jordan. The country borders Saudi Arabia to the east and south-east, Iraq to the north-east, Syria to the north and the West Bank and Israel to the west, sharing...
Israel
Israel
The State of Israel is a parliamentary republic located in the Middle East, along the eastern shore of the Mediterranean Sea...
,Lebanon
Lebanon
Lebanon , officially the Republic of LebanonRepublic of Lebanon is the most common term used by Lebanese government agencies. The term Lebanese Republic, a literal translation of the official Arabic and French names that is not used in today's world. Arabic is the most common language spoken among...
and Syria
Syria
Syria , officially the Syrian Arab Republic , is a country in Western Asia, bordering Lebanon and the Mediterranean Sea to the West, Turkey to the north, Iraq to the east, Jordan to the south, and Israel to the southwest....
. The branched inflorescence is one of several salvias thought to have inspired the design of the menorah. It grows to about 1 meter in height and width, and blooms in spring or early summer with pale yellow and white flowers in delicate whorls.
Biological properties
A group of Italian and Jordanian researchers isolated twenty-four new sesterterpenes, some of them with interesting biological activity due to their interaction with tubulin-tyrosine ligaseTubulin-tyrosine ligase
In enzymology, a tubulin-tyrosine ligase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are ATP, detyrosinated alpha-tubulin, and L-tyrosine, whereas its 3 products are alpha-tubulin, ADP, and phosphate....
(TTL), an enzyme involved in the tyrosination cycle of the C-terminal of tubulin, and inhibit TTL activity in cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...
cells.