Santa Fe, Isle of Youth
Encyclopedia
Santa Fe is the second largest city on Isla de la Juventud of Cuba
Cuba
The Republic of Cuba is an island nation in the Caribbean. The nation of Cuba consists of the main island of Cuba, the Isla de la Juventud, and several archipelagos. Havana is the largest city in Cuba and the country's capital. Santiago de Cuba is the second largest city...

.

The city is located 20 km south of Nueva Gerona
Nueva Gerona
Nueva Gerona is the capital city of the Isla de la Juventud special municipality of Cuba. The city is located between the hills of Caballos and Casas, about 3 km up the Río Casas, which provides a navigable waterway to the Caribbean Sea....

. It was the first settlement on the island, built around mineral springs.

(Note: there is also a Santa Fe which is a suburb in western Havana
Havana
Havana is the capital city, province, major port, and leading commercial centre of Cuba. The city proper has a population of 2.1 million inhabitants, and it spans a total of — making it the largest city in the Caribbean region, and the most populous...

.)

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