The Santa Fe Trail was a 19th-century transportation route through central North America that connected Missouri

Missouri

Missouri is a US state located in the Midwestern United States, bordered by Iowa, Illinois, Kentucky, Tennessee, Arkansas, Oklahoma, Kansas and Nebraska. With a 2010 population of 5,988,927, Missouri is the 18th most populous state in the nation and the fifth most populous in the Midwest. It...

 with Santa Fe

Santa Fe, New Mexico

Santa Fe is the capital of the U.S. state of New Mexico. It is the fourth-largest city in the state and is the seat of . Santa Fe had a population of 67,947 in the 2010 census...

, New Mexico

New Mexico

New Mexico is a state located in the southwest and western regions of the United States. New Mexico is also usually considered one of the Mountain States. With a population density of 16 per square mile, New Mexico is the sixth-most sparsely inhabited U.S...

. Pioneered in 1822 by William Becknell

William Becknell

William Becknell was a freight operator who established the Santa Fe Trail.Becknell was born in Amherst County, Virginia. He left Franklin, Missouri in September 1821 on his first trip to the western US with a load of freight to deliver to Santa Fe, New Mexico...

, it served as a vital commercial and military highway until the introduction of the railroad to Santa Fe in 1880. At first an international trade route between the United States and Mexico

Mexico

The United Mexican States , commonly known as Mexico , is a federal constitutional republic in North America. It is bordered on the north by the United States; on the south and west by the Pacific Ocean; on the southeast by Guatemala, Belize, and the Caribbean Sea; and on the east by the Gulf of...

, it was the 1846 U.S. invasion route of New Mexico during the Mexican–American War

Mexican–American War

The Mexican–American War, also known as the First American Intervention, the Mexican War, or the U.S.–Mexican War, was an armed conflict between the United States and Mexico from 1846 to 1848 in the wake of the 1845 U.S...

.

The route crossed Comancheria

Comancheria

The Comancheria is the name commonly given to the region of New Mexico, west Texas and nearby areas occupied by the Comanche before the 1860s.-Geography:...

, the territory of the Comanche

Comanche

The Comanche are a Native American ethnic group whose historic range consisted of present-day eastern New Mexico, southern Colorado, northeastern Arizona, southern Kansas, all of Oklahoma, and most of northwest Texas. Historically, the Comanches were hunter-gatherers, with a typical Plains Indian...

s, who demanded compensation for granting rights-of-way.