Scripps Genomic Health Initiative
Encyclopedia
The Scripps Genomic Health Initiative (SGHI) is a ground-breaking study aimed at understanding how personal genetic testing
influences and improves health.
Led by Dr. Eric Topol
, director of the San Diego-based Scripps Translational Science Institute, the 20-year initiative will determine whether patients make an effort to improve their lifestyle and get regular checkups after learning their genetic predisposition for many common diseases. Researchers will also assess the psychological impact of genomic testing, and whether those who do it are able to prevent or delay disease by taking action after getting their results.
The study was launched in October 2008 and will follow more than 10,000 adults. A consortium of health care, technology and research leaders have joined forces in the first-of-its-kind research study, including genetic test provider Navigenics
Inc., Affymetrix
and Microsoft
Corp.
Study participants receive a scan of their genome and a detailed analysis of their genetic risk for more than 20 health conditions that may be changed by lifestyle, including type 2 diabetes, Alzheimer’s disease, heart attack, obesity, and several types of cancer.
Said Peter Neupert, corporate VP for the Health Solutions Group at Microsoft:
Genetic testing
Genetic testing is among the newest and most sophisticated of techniques used to test for genetic disorders which involves direct examination of the DNA molecule itself. Other genetic tests include biochemical tests for such gene products as enzymes and other proteins and for microscopic...
influences and improves health.
Led by Dr. Eric Topol
Eric Topol
Eric J. Topol, M.D. is an American cardiologist, geneticist, and researcher. Much of Topol's career was spent at the Cleveland Clinic, where he served as chairman of cardiovascular medicine and founded the Cleveland Clinic Lerner College of Medicine...
, director of the San Diego-based Scripps Translational Science Institute, the 20-year initiative will determine whether patients make an effort to improve their lifestyle and get regular checkups after learning their genetic predisposition for many common diseases. Researchers will also assess the psychological impact of genomic testing, and whether those who do it are able to prevent or delay disease by taking action after getting their results.
The study was launched in October 2008 and will follow more than 10,000 adults. A consortium of health care, technology and research leaders have joined forces in the first-of-its-kind research study, including genetic test provider Navigenics
Navigenics
Navigenics, Inc. is a privately held personal genomics company, based in Foster City, California, that uses genetic testing to help people determine their individual risk for dozens of health conditions....
Inc., Affymetrix
Affymetrix
Affymetrix is a company that manufactures DNA microarrays; it is based in Santa Clara, California, United States. The company was founded by Dr. Stephen Fodor in 1992. It began as a unit in Affymax N.V...
and Microsoft
Microsoft
Microsoft Corporation is an American public multinational corporation headquartered in Redmond, Washington, USA that develops, manufactures, licenses, and supports a wide range of products and services predominantly related to computing through its various product divisions...
Corp.
Study participants receive a scan of their genome and a detailed analysis of their genetic risk for more than 20 health conditions that may be changed by lifestyle, including type 2 diabetes, Alzheimer’s disease, heart attack, obesity, and several types of cancer.
Said Peter Neupert, corporate VP for the Health Solutions Group at Microsoft:
"Personalized medicine stands to change the way people approach their health and wellness, as well as open up new genetic research opportunities."
See also
- Full Genome SequencingFull genome sequencingFull genome sequencing , also known as whole genome sequencing , complete genome sequencing, or entire genome sequencing, is a laboratory process that determines the complete DNA sequence of an organism's genome at a single time...
- Genetic testingGenetic testingGenetic testing is among the newest and most sophisticated of techniques used to test for genetic disorders which involves direct examination of the DNA molecule itself. Other genetic tests include biochemical tests for such gene products as enzymes and other proteins and for microscopic...
- Personal genomicsPersonal genomicsPersonal genomics is the branch of genomics concerned with the sequencing and analysis of the genome of an individual. The genotyping stage employs different techniques, including single-nucleotide polymorphism analysis chips , or partial or full genome sequencing...
- NavigenicsNavigenicsNavigenics, Inc. is a privately held personal genomics company, based in Foster City, California, that uses genetic testing to help people determine their individual risk for dozens of health conditions....
- AffymetrixAffymetrixAffymetrix is a company that manufactures DNA microarrays; it is based in Santa Clara, California, United States. The company was founded by Dr. Stephen Fodor in 1992. It began as a unit in Affymax N.V...
- MicrosoftMicrosoftMicrosoft Corporation is an American public multinational corporation headquartered in Redmond, Washington, USA that develops, manufactures, licenses, and supports a wide range of products and services predominantly related to computing through its various product divisions...
- Eric TopolEric TopolEric J. Topol, M.D. is an American cardiologist, geneticist, and researcher. Much of Topol's career was spent at the Cleveland Clinic, where he served as chairman of cardiovascular medicine and founded the Cleveland Clinic Lerner College of Medicine...