Sea turtle tornovirus 1
Encyclopedia
Sea turtle tornovirus 1 is a single stranded DNA virus that was isolated from a turtle with fibropapillomatosis
Fibropapillomatosis
Fibropapillomatosis is a condition characterized by the presence of fibropapillomas, neoplasms consisting of both the epidermal and dermal skin layers.-In sea turtles:...

 in 2009.

Virology

The genome is circular and ~1.8 kilobases in length with a G+C content of ~50%. It has at least three open reading frames (ORF 1, 2, 3) and two others (ORF 4 and 5) may also be present. The genome is of negative polarity.

ORF 1 posses a putative nuclear localization signal at its N terminal. ORF 2 has some homology to the viral protein 2 of chicken anaemia virus. ORF 3 has no homology to any known protein. Similarly neither ORF 4 or 5 have any homology with any known protein. The functions of these proteins is not known.

A TATA box (sequence - TATAAA) and a poly adenosine signal (sequence - AATAAA) are present in the genome.

Taxonomy

The final classification of this virus has yet to be decided.

It has a low level of homology to the Circovirus chicken anemia virus.

Clinical

The virus can be isolated from the blood and all the major organs as well as the fibropapiloma.
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