Secretin receptor
Encyclopedia
Human secretin receptor (gene name SCTR) is a G protein-coupled receptor
which binds secretin
and is the leading member (i.e., first cloned) of the class B GPCR subfamily.
with Pituitary adenylate cyclase activating peptide
.
G protein-coupled receptor
G protein-coupled receptors , also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors , comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal...
which binds secretin
Secretin
Secretin is a hormone that controls the secretions into the duodenum, and also separately, water homeostasis throughout the body. It is produced in the S cells of the duodenum in the crypts of Lieberkühn...
and is the leading member (i.e., first cloned) of the class B GPCR subfamily.
Interactions
Secretin receptor has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Pituitary adenylate cyclase activating peptide
Pituitary adenylate cyclase activating peptide
Pituitary adenylate cyclase-activating polypeptide also known as PACAP is a protein that in humans is encoded by the ADCYAP1 gene. PACAP is similar to vasoactive intestinal peptide. One of its effects is to stimulate enterochromaffin-like cells. It binds to vasoactive intestinal peptide receptor.-...
.